Diagnosis and Treatment of Pulmonary Hypertension

Part I. Fundamentals of Pulmonary Hypertension

1. Clinical Classification
Koichiro Tatsumi

2. Diagnosis: Imaging
Nobuhiro Tahara, Tomohisa Nakamura, Hidetoshi Chibana, Eita Kumagai, Yoichi Sugiyama, Munehisa Bekki, Akihiro Honda, Atsuko Tahara, Sachiyo Igata, Yoshihiro Fukumoto

Part II. Pathophysiology and Genetics

3. Pathogenic and Therapeutic Role of MicroRNA in Pulmonary Arterial Hypertension
Aleksandra Babicheva, Kimberly M. McDermott, Samuel C. Williams, Allison M. Yee, Swetaleena Dash, Marisela Rodriquez, Nadia Ingabire, Ayako Makino, Jason X. -J. Yuan

4. Sex Hormones
Kaori Oshima, Masahiko Oka

5. Rho-Kinase as a Therapeutic Target for Pulmonary Hypertension
Kimio Satoh, Koichiro Sugimura, Hiroaki Shimokawa

6. The Unique Property of the Pulmonary Artery Regarding the Smooth Muscle Effects of Proteinase-Activated Receptor 1: The Possible Contribution to the Pathogenesis of Pulmonary Hypertension
Katsuya Hirano

7. Animal Models with Pulmonary Hypertension
Kohtaro Abe

8. Human Pathology
Hatsue Ishibashi-Ueda, Keiko Ohta-Ogo

9. Pathophysiology and Genetics: BMPR2
Yoshihide Mitani

Part III. Treatment of Pulmonary Arterial Hypertension (PAH)

10. Prostacyclin
Satoshi Akagi

11. Targeting the NO-sGC-cGMP Pathway in Pulmonary Arterial Hypertension
Hiroshi Watanabe, Quang-Kim Tran

12. Endothelin Receptor Antagonist
Noriaki Emoto

13. Lung Transplantation
Hiroshi Date

Part IV. Treatment of Chronic Thromboembolic Pulmonary Hypertension (CTEPH)

14. Medical Therapy for Chronic Thromboembolic Pulmonary Hypertension
Toru Satoh

15. Balloon Pulmonary Angioplasty
Hiromi Matsubara, Aiko Ogawa

16. Pulmonary Endarterectomy for Chronic Thromboembolic Pulmonary Hypertension
Hitoshi Ogino

Part V. Right Ventricular Function

17. Right Ventricular Function
Kaoru Dohi, Norikazu Yamada, Masaaki Ito

Nyckelord: Medicine & Public Health, Cardiology, Pneumology/Respiratory System, Cardiac Surgery