Antibiotic Pharmacokinetic/Pharmacodynamic Considerations in the Critically Ill

1. Basic Pharmacokinetic Principles
Kashyap Patel, Carl M. Kirkpatrick

2. Antibiotic Pharmacodynamics
Fekade B. Sime, Jason A. Roberts

3. Physiological Manifestations of Critical Illness
Federico Pea

4. Dosing in Obese Critically Ill Patients
Maya Hites, Fabio Silvio Taccone

5. Hypoalbuminaemia and Altered Protein Binding
Adrian Brink

6. Acute Kidney Injury and Renal Replacement Therapy
Gordon Y. S. Choi, Gavin M. Joynt

7. Augmented Renal Clearance
João Pedro Baptista

8. Antibiotic Dosing During Extracorporeal Membrane Oxygenation
Mohd. H. Abdul-Aziz, Kiran Shekar, Jason A. Roberts

9. Therapeutic Drug Monitoring: More Than Avoiding Toxicity
Jana Stojanova, Sonia Luque

10. Generic and Optimized Antibacterial Dosing Strategies in the Critically Ill
Jan J. Waele

11. Antifungal PK/PD in the Critically Ill
Roger J. M. Brüggemann, Dylan W. Lange, Jan-Willem C. Alffenaar

12. Antibiotic Dosing in Pediatric Critically Ill Patients
Pieter A. J. G. Cock, Karel Allegaert, Matthew W. Linakis, Catherine M. T. Sherwin

13. Antibiotic Stewardship in the Intensive Care Unit
M. Gilchrist, E. T. Brannigan, G. Satta, M. Laundy

Nyckelord: Medicine & Public Health, Pharmacotherapy, Pharmaceutical Sciences/Technology