Proteases in Human Diseases

Part I. Involvement of Proteases in Various Diseases

1. Matrix Metalloproteinases in Breast Carcinoma
Irena Ranogajec

2. Multifaceted Role of Matrix Metalloproteases on Human Diseases
Soumitra Roy, Asmita Pramanik, Tapati Chakraborti, Sajal Chakraborti

3. Complex Mechanisms of Matrix Metalloproteinases Involvement in Endometrial Physiology and Pathology—An Update
Cornelia Amalinei, Irina-Draga Căruntu, Simona Eliza Giuşcă, Raluca Anca Balan

4.
Plasmodium Proteases as Therapeutic Targets Against Malaria
Asrar Alam

5. Role of Metalloproteinases in Melanoma Growth and Progression
Cinthia Figueiredo, Ana Candida Araujo e Silva

6. Cysteine Cathepsins: In Health and Rheumatoid Arthritis
Nalini Ganesan

7. Proteases in Neuropathophysiology
Abhijit Sarkar, Sumit Ghosh, Sayanta Dutta, Parames C. Sil

8. Proteases in Wound Healing and Immunity
Namrata Singh, Debasish Bhattacharyya

9. Translating the Knowledge of Functional Dynamics Toward Designing Inhibitors of BACE1, a Key Aspartate Protease in Alzheimer’s Disease
Sandipan Chakraborty, Soumalee Basu

10. Serine Proteases and Their Inhibitors in Human Health and Disease
K. Vijaya Rachel, Gandreddi V. D. Sirisha

11. Metalloproteases and Human Diseases: The Astacin Family
Sibani Chakraborty, Asim K. Bera, Ankur Chaudhuri, Satyajit Sen

12. Proteases of Parasitic Helminths: Their Metabolic Role in Establishment of Infection in the Host
Veena Tandon, Bidyadhar Das, Shakti Kumar

13. Natural Polyphenols as Prospective Inhibitors for MMPs Remodeling in Human Diseases
Yashika Rustagi, Aditi Jain, Sharad Saxena, Vibha Rani

14. Autophagic Proteases: Functional and Pathophysiological Aspects
Pijush Kanti Pramanik, Dibyendu Paik, Asmita Pramanik, Md Nur Alam, Partha Das, Tapati Chakraborti

15. ADAM and ADAMTS Family of Metalloproteinases: Role in Cancer Progression and Acquisition of Hallmarks
Rajakishore Mishra, Siddavaram Nagini

16. Role of Proteases in Lung Disease: A Brief Overview
Sajal Chakraborti, Jaganmay Sarkar, Pijush Kanti Pramanik, Tapati Chakraborti

17. Caspases: Moonlighting Proteins with Theranostic Potential
Siddavaram Nagini, Satwinderjeet Kaur

18. Functional Aspects of Activated Protein C (APC) in Regulating Homeostasis and Disease
Ramesh Prasad, Abhishek Roy, Prosenjit Sen

Part II. Role of Proteases in Cardiovascular Diseases

19. Role of Calpains (Calcium-Dependent Proteases) on Coronary Artery Disease and Metabolic Syndrome
Brittany A. Potz, M. Ruhul Abid, Frank W. Sellke

20. Role of Matrix Metalloproteinases in the Development and Progression of Atherosclerosis
Karina Di Gregoli, Jason Lee Johnson

21. Protease Cathepsins in Cardiomyopathy: From Mechanism to Intervention
Rui Guo, Sreejayan Nair

22. Cysteine-Dependent Aspartate-Specific Proteases in Coronary Artery Disease
Gundapaneni Kishore Kumar, Hanumanth Surekha Rani

23. Association of Matrix Metalloproteinases with CVD: Functional Aspects
Veena Dhawan, Riyaz Ahmad Rather

24. microRNAs-Mediated MMPs Regulation: Novel Mechanism for Cardiovascular Diseases
Sharad Saxena, Yashika Rustagi, Aditi Jain, Sonali Dubey, Vibha Rani

Nyckelord: Biomedicine, Human Physiology, Molecular Medicine, Pharmaceutical Sciences/Technology, Cancer Research