Tumor Dormancy, Quiescence, and Senescence, Volume 2

Part I. Molecular Mechanisms

1. Asymmetric Dimethylarginine Accelerates Cellular Senescence
Fotunato Scalera, Stefanie M. Bode-Böger

2. Membrane-Derived Extracellular Vesicles from Endothelial Progenitor Cells Activate Angiogenesis
Vincenzo Cantaluppi, Federico Figliolini, Maria Chiara Deregibus, Giovanni Camussi

3. Induction of P21-Dependent Senescence: Role of NAE Inhibitor MLN4924
Yongfu Pan, Yi Sun, Lijun Jia

4. Regulation of the Novel Senescence Pathway by SKP2 E3 Ligase
Guocan Wang, Yuan Gao, Li Chen, Ying-Jan Wang, Hui-Kuan Lin

5. Oncogene-Induced Senescence: Role of Mitochondrial Dysfunction
Olga Moiseeva, Gerardo Ferbeyre

6. Interleukin-6 Induces Premature Senescence Involving Signal Transducer and Activator of Transcription 3 and Insulin-Like Growth Factor-Binding Protein 5
Hirotada Kojima, Hiroyuki Kunimoto, Toshiaki Inoue, Koichi Nakajima

7. A Role for the Nuclear Lamina Shape in Cell Senescence and Aging
Christiaan H. Righolt, Vered Raz

8. Upregulation of Alpha-2-Macroglobulin in Replicative Senescence
Li Wei Ma, Guo Dong Li, Tan Jun Tong

9. Elevation of Ceramide in Senescence: Role of Sphingolipid Metabolism
Mark E. Venable

10. Molecular Signals Underlying Hair Follicle Morphogenesis and Cutaneous Regeneration
Xusheng Wang, Yaojiong Wu

11. Role of Chromatin-Remodeling Factor Jun Dimerization Protein 2 (JDP2) in Cellular Senescence
Kazunari K. Yokoyama, Kung-Kai Kuo

12. Induction of Cellular Senescence: Role of Mitogen-Activated Protein Kinase-Interacting Kinase 1
Samira Ziaei, Naoko Shimada

13. Mechanisms of Premature Cell Senescence
Julien Maizel, Jun Chen, Michael S. Goligorsky

Part II. Tumor and Cancer

14. Nuclear Protein Pirin Negates the Cellular Senescence Barrier Against Cancer Development
Silvia Licciulli, Myriam Alcalay

15. Defects in Chromatin Structure and Diseases
Umberto Galderisi, Gianfranco Peluso

16. The Role of Fibrosis in Tumor Progression and the Dormant to Proliferative Switch
Lara H. Touny, Dalit Barkan, Jeffrey E. Green

17. Diagnosis of Branchial Cyst Carcinoma: Role of Stem Cells and Dormancy
Athanassios Kyrgidis

18. Function of the ING Proteins in Cancer and Senescence
Uyen M. Tran, Uma Rajarajacholan, Karl Riabowol

19. Premalignancy and Cellular Senescence
Hussein A. Abbas, Raya Saab

20. Loss of Cdh1 Triggers Premature Senescence in Part via Activation of Both the RB/E2F1 and the CLASPIN/CHK1/P53 Tumor Suppressor Pathways
Shavali Shaik, Pengda Liu, Zhiwei Wang, Wenyi Wei

21. Suppression of Premature Senescence and Promotion of Metastatic Transformation: Role of Reduced TGF-Beta Signaling in Human Cancer Progression
Shu Lin, Lu-Zhe Sun

22. Senescence Escape in Melanoma: Role of Spleen Tyrosine Kinase SYK
Marcel Deckert, Sophie Tartare-Deckert

23. Micrometastatic Cancer Cells: Role of Tumor Dormancy in Non-small Cell Lung Cancer (NSCLC)
Stefan Werner, Michaela Wrage, Harriet Wikman

24. Quiescent CD4+ T Cells Inhibit Multiple Stages of HIV Infection
Jerome A. Zack, Dimitrios N. Vatakis

Part III. Stem Cells and Cancer Stem Cells

25. Senescent-Derived Pluripotent Stem Cells Are Able to Redifferentiate into Fully Rejuvenated Cells
Ollivier Milhavet, Jean-Marc Lemaitre

26. The Transcription Factor GATA2 Regulates Quiescence in Haematopoietic Stem and Progenitor Cells
Neil P. Rodrigues, Alex J. Tipping

27. Dormancy and Recurrence of Cancer Stem Cells in Bone: Role of Bone Morphogenetic Proteins
Sambad Sharma, Fei Xing, Kounosuke Watabe

28. Role of Microenvironment in Regulating Stem Cell and Tumor Initiating Cancer Cell Behavior and Its Potential Therapeutic Implications
Ana Krtolica

Nyckelord: Life Sciences, Life Sciences, general, Biomedicine general, Medicine/Public Health, general