Structure and Physics of Viruses

Part I. The Viral Machine

1. Introduction: The Structural Basis of Virus Function
Mauricio G. Mateu

2. The Basic Architecture of Viruses
José R. Castón, José L. Carrascosa

Part II. Determination of the Structure and Physical Properties of Viruses

3. Conventional Electron Microscopy, Cryo-Electron Microscopy and Cryo-Electron Tomography of Viruses
José R. Castón

4. X-Ray Crystallography of Viruses
Nuria Verdaguer, Damià Garriga, Ignacio Fita

5. Nuclear Magnetic Resonance Spectroscopy to Study Virus Structure
José L. Neira

6. Fluorescence, Circular Dichroism and Mass Spectrometry as Tools to Study Virus Structure
José L. Neira

7. Combined Approaches to Study Virus Structures
Daniel Badia-Martinez, Hanna M. Oksanen, David I. Stuart, Nicola G. A. Abrescia

8. Atomic Force Microscopy of Viruses
Pedro J. Pablo

9. Optical Tweezers to Study Viruses
J. Ricardo Arias-Gonzalez

Part III. Structural Foundations of Virus Properties and Functions

10. Assembly of Simple Icosahedral Viruses
José M. Almendral

11. Structure and Assembly of Complex Viruses
Carmen San Martín

12. Nucleic Acid Packaging in Viruses
Ana Cuervo, María I. Daudén, José L. Carrascosa

13. Virus Maturation
Laura R. Delgui, José F. Rodríguez

14. Virus Morphogenesis in the Cell: Methods and Observations
Cristina Risco, Isabel Fernández de Castro

15. Virus-Receptor Interactions and Receptor-Mediated Virus Entry into Host Cells
José M. Casasnovas

16. Entry of Enveloped Viruses into Host Cells: Membrane Fusion
Vicente Más, José A. Melero

17. Bacteriophage Receptor Recognition and Nucleic Acid Transfer
Carmela Garcia-Doval, Mark J. Raaij

18. Mechanical Properties of Viruses
Pedro J. Pablo, Mauricio G. Mateu

19. Theoretical Studies on Assembly, Physical Stability and Dynamics of Viruses
Antoni Luque, David Reguera

Part IV. Applied Structural and Physical Virology

20. Antiviral Agents: Structural Basis of Action and Rational Design
Luis Menéndez-Arias, Federico Gago

21. Design of Novel Vaccines Based on Virus-Like Particles or Chimeric Virions
Juan Bárcena, Esther Blanco

22. Nanoscale Science and Technology with Plant Viruses and Bacteriophages
Alexander M. Bittner, José María Alonso, Marcin Ł. Górzny, Christina Wege

Nyckelord: Biomedicine, Biomedicine general, Protein Structure, Virology, Mechanics