GPCR Signalling Complexes – Synthesis, Assembly, Trafficking and Specificity

1. ER-Bound Steps in the Biosynthesis of G Protein-Coupled Receptors
Christian Nanoff, Michael Freissmuth

2. Role of Chaperones in G Protein Coupled Receptor Signaling Complex Assembly
Denis J. Dupré, Maha M. Hammad, Patrick Holland, Jaime Wertman

3. GPCR Oligomerization: Contribution to Receptor Biogenesis
Kathleen Craenenbroeck

4. The Functional Size of GPCRs – Monomers, Dimers or Tetramers?
Darlaine Pétrin, Terence E. Hébert

5. Regulation of Post-Golgi Traffic of G Protein-Coupled Receptors
Guangyu Wu

6. Regulated GPCR Trafficking to the Plasma Membrane: General Issues and the CCR5 Chemokine Receptor Example
Hamasseh Shirvani, Gabriel Gätà, Stefano Marullo

7. Regulatory Processes Governing the Cell Surface Expression of LH and FSH Receptors
Deborah L. Segaloff

8. Chaperone-Mediated Assembly of G Protein Complexes
Barry M. Willardson, Christopher M. Tracy

9. Synthesis and Assembly of G Protein βγ Dimers: Comparison of In Vitro and In Vivo Studies
Jane Dingus, John D. Hildebrandt

10. Preferential Assembly of G-αβγ Complexes Directed by the γ Subunits
Janet D. Robishaw

11. G Protein Trafficking
Philip B. Wedegaertner

12. Differential Assembly of GPCR Signaling Complexes Determines Signaling Specificity
Pascal Maurice, Abla Benleulmi-Chaachoua, Ralf Jockers

13. GPCR and Voltage-Gated Calcium Channels (VGCC) Signaling Complexes
Christophe Altier

14. Pharmacological Chaperones Correct Misfolded GPCRs and Rescue Function: Protein Trafficking as a Therapeutic Target
Guadalupe Maya-Núñez, Alfredo Ulloa-Aguirre, Jo Ann Janovick, P. Michael Conn

Nyckelord: Biomedicine, Biomedicine general, Pharmacology/Toxicology, Receptors, Medical Biochemistry