Circulating Nucleic Acids in Plasma and Serum

1. Current Developments in Circulating Nucleic Acids in Plasma and Serum
Peter B. Gahan

2. Reflections on a Life of CNAPS: From Circulating DNA to the Virtosome
Maurice Stroun

3. Circulating Tumor-Related DNA Alterations as Prostate Cancer Biomarkers
Laurent Lessard, Eiji Sumami, Dave S.B. Hoon

4. Parallel Tagged 454 Sequencing for the Characterization of Circulating DNA
Maniesh Vaart, Dmitry V. Semenov, Elena V. Kuligina, Vladimir A. Richter, Piet J. Pretorius

5. Advanced Analysis of Human Plasma Circulating DNA Sequences Produced by Parallel Tagged Sequencing on the 454 Platform
Maniesh Vaart, Dmitry V. Semenov, Elena V. Kuligina, Vladimir A. Richter, Piet J. Pretorius

6. Concentration and Distribution of Single-Copy β-Actin Gene and LINE-1 Repetitive Elements in Blood of Lung Cancer Patients
Anastasia A. Ponomaryova, Elena Y. Rykova, Nadezhda V. Cherdyntseva, Tatiana E. Skvortsova, Anna V. Cherepanova, Evgeniy S. Morozkin, Vladislav A. Mileiko, Nikolai V. Litvjakov, Alexey Y. Dobrodeev, Alexander A. Zav’yalov, Sergey A. Tuzikov, Elena D. Chikova, Valentin V. Vlassov, Pavel P. Laktionov

7. Plasma DNA Methylation Analysis in Predicting Short-Term Recurrence of Surgical Patients with Non-small Cell Lung Cancer (NSCLC)
Qingqing Ding, Yuan Mu, Shiyang Pan, Yongqian Shu, Shijiang Zhang, Bingfeng Zhang, Hong Wang, Li Gao, Wenying Xia, Jian Xu, Meijuan Zhang, Yuanyuan Zhang, Yan Cao, Shan Lu

8. Blood Based Methylated DNA and Tumor-Specific Protein Analysis in Gastric Cancer Diagnostics
Elena V. Elistratova, Petr I. Shelestyuk, Valentina I. Permyakova, Elena D. Chikova, Sergey A. Tuzikov, Valentin V. Vlassov, Pavel P. Laktionov, Elena Y. Rykova

9. Increase in Circulating MicroRNA Levels in Blood of Ovarian Cancer Patients
Carina Roth, Sabine Kasimir-Bauer, Martin Heubner, Klaus Pantel, Heidi Schwarzenbach

10. The Course of Circulating Nucleosomes in Liver Cancer Patients Undergoing Transarterial Chemoembolization Therapy
Nikolaus Kohles, Dorothea Nagel, Dietrich Jüngst, Jürgen Durner, Petra Stieber, Stefan Holdenrieder

11. Presence of Nucleosomes in Cerebrospinal Fluid of Glioblastoma Patients – Potential for Therapy Monitoring
Stefan Holdenrieder, Andreas Spuler, Michael Tischinger, Dorothea Nagel, Petra Stieber

12. Circulating Nucleosomes and DNAse in Breast Cancer Patients During Neoadjuvant Chemotherapy
Oliver J. Stoetzer, Debora M.I. Fersching, Stefan Holdenrieder

13. Circulating Nucleosomes in Cancer Patients with Liver Metastases Undergoing Selective Internal Radiation Therapy Using Yttrium-90 Labelled Microspheres
Yvonne Fehr, Stefan Holdenrieder, Ralf-Thorsten Hoffmann, Klaus Tatsch, Tobias Jakobs, Dorothea Nagel, Petra Stieber

14. H3K9me3/H4K20me3 Ratio in Circulating Nucleosomes as Potential Biomarker for Colorectal Cancer
Ugur Deligezer, Elif Z. Akisik, Ebru E. Akisik, Müge Kovancilar, Dursun Bugra, Nilgün Erten, Stefan Holdenrieder, Nejat Dalay

15. Functionality of CNAPS in Cancer: The Theory of Genometastasis
Dolores C. García-Olmo, Hector Guadalajara, Carolina Dominguez-Berzosa, María G. Picazo, Mariano García-Arranz, Damián García-Olmo

16. Circulating Fetal DNA/RNA in Maternal Plasma for Aneuploidy Detection
Y. K. Tong, R.W.K. Chiu, Y.M.D. Lo

17. A “Fluid-Agnostic” Approach to Analysis of Fetal and Neonatal Developmental Gene Expression
Jill L. Maron, Diana W. Bianchi

18. Non-invasive Prenatal Diagnosis: An Epigenetic Approach to the Detection of Common Fetal Chromosome Disorders by Analysis of Maternal Blood Samples
Maj A. Hultén, Elisavet A. Papageorgiou, Floriana Della Ragione, Maurizio D’Esposito, Nigel Carter, Philippos C. Patsalis

19. Comparative Study of Extracellular DNA by FISH
Evgeniy S. Morozkin, Ekaterina M. Loseva, Vladislav A. Mileiko, Kira S. Zadesenets, Nikolay B. Rubtsov, Valentin V. Vlassov, Pavel P. Laktionov

20. An Additional Pre-amplification Step for the Early Determination of Fetal RHD from Maternal Plasma
Tadeja Dovč-Drnovšek, Nataša Toplak, Irena Bricl, Tanja Blejec, Minka Kovač, Primož Rožman

21. The Correlation of Circulating Cell-Free DNA, Cell-Free Fetal DNA and MicroRNA 325 Levels to Clinical Characteristics and Laboratory Parameters in Pre-eclampsia
Levente Lázár, Bálint Nagy, Attila Morvarec, János Rigó

22. Comparison of Plasma Cell-Free DNA Levels with Gene Expression Profiles of Peripheral Blood Cells During Haemodialysis
Ales Horinek, Ales Panczak, Magdalena Mokrejsova, Katarina Rocinova, Marie Korabecna, Dalibor Cerny, Vladimir Tesar

23. Low-Molecular-Weight DNA of Blood Plasma as an Indicator of Pathological Processes
Irina N. Vasilyeva, Tatyana V. Ivtchik, Igor A. Voznyuk

24. The Clinical Significance of Plasma DNA Quantification for Quake Trauma Patients
Dan Chen, Shiyang Pan, Shijiang Zhang, Peijun Huang, Wenying Xia, Erfu Xie, Bing Gu, Fang Wang, Jian Xu, Ting Xu, Yachun Lu, Di Yang, Shan Lu

25. Methylated Cell-Free DNA In Vitro and In Vivo
Tatyana E. Skvortsova, Olga E. Bryzgunova, Alena O. Lebedeva, Viktoria V. Mak, Valentin V. Vlassov, Pavel P. Laktionov

26. Circadian Rhythmicity and Clearance of Cell-Free DNA in Human Plasma
Marie Korabecna, Ales Horinek, Nikola Bila, Sylvie Opatrna

27. Fragments of Cell-Free DNA (cfDNA) Enhance Transcription Activity in Human Mesenchymal Stem Cells (hMSCs) and Inhibit Their In Vitro Differentiation
Elena M. Malinovskaya, Svetlana V. Kostyuk, Aleksey V. Ermakov, Marina S. Konkova, Tatjana D. Smirnova, Larisa V. Kameneva, Liudmila V. Efremova, Anna Yu. Alekseeva, Liudmila N. Lyubchenko, Natalya N. Veiko

28. Cell-Surface-Bound DNA Inhibits Poly(I:C)-Activated IL-6 and IL-8 Production in Human Primary Endothelial Cells and Fibroblasts
Anna V. Cherepanova, Alexander V. Bushuev, Valentin V. Vlassov, Pavel P. Laktionov

29. Accumulating Fragments of Extracellular DNA (ecDNA) Influence Rat Primary Cerebellum Granule Cell Culture
Liudmila V. Efremova, Svetlana V. Kostyuk, Leonid G. Khaspekov, Natalya N. Veiko

30. Cell Free DNA (cfDNA) Influences Nitric Oxide and ros Levels in Human Endothelial Cells
Anna Yu. Alekseeva, Natalia V. Bulycheva, Svetlana V. Kostyuk, Tatjana D. Smirnova, Natalya N. Veiko

31. Development of the Adaptive Response and Bystander Effect Induced by Low-Dose Ionising Radiation in Human Mesenchymal Stem Cells
Aleksey V. Ermakov, Marina S. Konkova, Svetlana V. Kostyuk, Tatjana D. Smirnova, Liudmila V. Efremova, Liudmila N. Lyubchenko, Natalya N. Veiko

32. Extracellular RNA as Regulators of Cellular Processes
Dmitry V. Semenov, Grigory A. Stepanov, Dmitry N. Baryakin, Olga A. Koval, Elena V. Kuligina, Vladimir A. Richter

33. Microvesicles Circulating in Plasma of Rats Contain DNA: Are These Small Vesicles a Main Source of Cell-Free DNA in Plasma?
Gemma Serrano-Heras, Damián García-Olmo, Dolores C. García-Olmo

34. Rapid Isolation and Detection of Cell Free Circulating DNA and Other Disease Biomarkers Directly from Whole Blood
Rajaram Krishnan, Michael J. Heller

35. Yields of Viral and Circulating Cell-Free Nucleic Acids Using the QIAamp® Circulating Nucleic Acid Kit
Martin Horlitz, Tanja Hartinger, Simone Graf, Annabelle Lucas, Annette Nocon, Markus Sprenger-Haussels

36. Comparison of Nucleosomes and Quantitative PCR Using Diverse DNA Isolation Methods
Michael Fleischhacker, Bernd Schmidt, Sabine Weickmann, Debora M.I. Fersching, Gloria S. Leszinski, Barbara Siegele, Oliver J. Stoetzer, Stefan Holdenrieder

37. MicroRNA Analysis in the Spinal Fluid of Alzheimer Patients: A Methodological Feasibility Study
Argonde Harten, Joyce Mulders, Cagla Çevik, Maartje Kester, Philip Scheltens, Wiesje Flier, Cees Oudejans

Nyckelord: Biomedicine, Cancer Research, Human Genetics, Nucleic Acid Chemistry, Biotechnology