Basic and Applied Aspects

1. Purification of Hepatoblasts from Fetal Mouse Livers by Using a Temperature-Reversible Gelation Polymer and Their Application in Regenerative Medicine
Koichiro Yori, Toru Koike, Nobuyoshi Shiojiri

2. Computer Aided Rational Design of Biochemical Systems
Hiroyuki Kurata

3. DNA Microarray in Nutrigenomics and Cancer Prevention Research: Elucidating Molecular Signatures of Cancer Preventive Phytochemicals
Thomas T. Y. Wang

4. DNA Microarray Technology Evaluation of Effect of Dietary Intake of Crude Rice Glycosphingolipids in Mice
Jun Shimizu

5. Integrated Pathway Analysis of Genome-Wide Expression Changes Associated with Serum-Free Suspension Adaptation of an Antibody-Producing Chinese Hamster Ovary (CHO) Cell Line
Yung-Shyeng Tsao, Ankit A. Merchant, Aaron Meyer, Zhong Liu, Marsha Smith, Diane Levitan, Eric Gustafson

6. Affordable Mab by Ensuring Low Cog
Bjorn Hammarberg, Bo Forsberg

7. Evaluation of Neurotoxicity of Environmental Chemicals Using Neural Stem Cells and Neuroblastoma Cells
Masami Ishido

8. Integration of Endothelial Cell-Covered Hepatocyte Spheroids for Construction of Vascularized Liver Tissue
Masakazu Inamori, Hiroshi Mizumoto, Toshihisa Kajiwara

9. Characterization of Cell-Sized Vesicles Induced from Human Lymphoid Cell Lines
Makoto Yamanaka, Shigeki Nakamura, Aiko Inoue, Takashi Yasuda, Yuichi Inoue, Hiroharu Kawahara

10. Dendrimer-Immobilized Culture Surface as a Tool to Promote Aggregate Formation of Anchorage-Dependent Cells
Mee-Hae Kim, Masahiro Kino-oka, Jun-ichi Miyazaki, Masahito Taya

11. Advantage of Alagln as an Additive to Cell Culture Medium
Yasufumi Imamoto, Hisaya Tanaka, Ken Takahashi, Yoshinobu Konno, Toshiyuki Suzawa

12. Supplementation of Phosphatidylcholine Protects the Hybridoma Cells from Apoptosis Induced by Serum Withdrawal
Beng Ti Tey, Kah Choon Yap, Hideki Yamaji, Abdul Manaf Ali, Wen Siang Tan

13. Monoclonal Antibody Productivity of Hybridoma Cells Under Active Hypothermic Growth Condition
Beng Ti Tey, Sun Li Chong, Michelle Y. T. Ng, Duen Gang Mou, Saw Hoon Lim, Abdul Manaf Ali

14. Efficient Selection of Cell Clones with Higher Productivity in the Production of Recombinant Human Monoclonal Antibodies
Ayako Ohshima, Yumiko Takamatsu, Koichi Yamamot, Hiroyuki Saitoh

15. Continuous Cell Production from Three Dimensional Hematopoietic Microenvironment in Polyurethane Foam
Tadasu Jozaki, Kentarou Aoki, Hiroshi Mizumoto, Toshihisa Kajiwara

16. A New Approach for Drug Discovery and Differentiation Study Using Cutting-Edge 3d Cell Culture System
Fujiko Ozawa, Yoshitaka Miyagawa, Masami Hiroyama, Nobutaka Kiyokawa, Akihiro Umezawa, Akito Tanoue, Satoru Tanaka

17. Dimensional Cell Culture Dish for In Vivo-Like Cell Culture
Y. Furutani, T. Tamura, M. Kodama

18. Characterization of the Erythropoietin (EPO) Protein Production in the Recombinant Human Cultured Cells, in which the Exogenous EPO Gene was Introduced into Hypoxanthine Phosphoribosyl Transferase (HPRT) Gene Locus
Toshiaki Banzai, Yukiko Koyama, Shuji Sonezaki

19. Development of Protein High Expression System by Using Fructose Metabolism
Yuriko Tsukamoto, Shigeki Nakamura, Aiko Inoue, Norikazu Nishino, Yuichi Inoue, Hiroharu Kawahara

20. Controlling Fucosylation Levels of Antibodies with Osmolality during Cell Culture
Yoshinobu Konno, Yuki Kobayashi, Ken Takahashi, Eiji Takahashi, Shinji Sakae, Masako Wakitani, Toshiyuki Suzawa, Keiichi Yano, Masamichi Koike, Kaori Wakamatu, Shinji Hosoi

21. Comparison of Immunoresponses Between Cecal Patch Cells and Peyer’s Patch Cells Stimulated by Bacterial Components
Takuma Konno, Akira Hosono, Yasuhiro Hiramatsu, Satoshi Hachimura, Kyoko Takahashi, Shuichi Kaminogawa

22.
Conjugate of β-Lactoglobulin with Carboxymethyl Dextran Increased the Antigen-Specific IgG1 Production, While It Decreased IgE Production Compared with Native β-Lactoglobulin

Tadashi Yoshida, Yuko Shigihara, Manami Nakamura, Makoto Hattori

23. Anti-Inflammatory Action of Epigallocatechin-3-Gallate at a Physiological Concentration through the 67-KDA Laminin Receptor in Lipopolysaccharide-Stimulated Raw264.7 Cells
Byun Eui Hong, Yoshinori Fujimura, Koji Yamada, Hirofumi Tachibana

24. Enhancement of Antibody Production using Solution after Antibody Purification: Application of Spent Medium for Antibody Production
Akiko Ogawa, Sadaharu Fukui, Satoshi Terada

25. Production of Human Monoclonal Antibodies Against FC Epsilon Receptor I Alpha by Combining In Vitro Immunization with Phage Display
Kosuke Tomimatsu, Shin-ei Matsumoto, Makiko Yamashita, Kiichiro Teruya, Yoshinori Katakura, Shigeru Kabayama, Sanetaka Shirahata

26. Enhancement of Hepatocyte Function Through Heterotypic Cell-Cell Interactions Using E-Cadherin-Expressing NIH3T3 Cells
Akira Ito, Takehiko Kiyohara, Yoshinori Kawabe, Hiroyuki Ijima, Masamichi Kamihira

27. Magnetic Cell-Patterning for Tissue Engineering
Hirokazu Akiyama, Akira Ito, Yoshinori Kawabe, Masamichi Kamihira

28. Magnetic Force-Based Tissue Engineering of Skeletal Muscle for Bio-Actuator
Yasunori Yamamoto, Masahiro Kato, Akira Ito, Yoshinori Kawabe, Kazunori Shimizu, Eiji Nagamori, Masamichi Kamihira

29. Fabrication of Skeletal Muscle Tissue from C2C12 Myoblast Cell Towards the Use as Bio-Actuator
Hideaki Fujita, Kazunori Shimizu, Eiji Nagamori

30. Retroviral Vectors Pseudotyped with Chimeric Vesicular Stomatitis Virus Glycoprotein for Antibody-Dependent Gene Transduction
Yujiro Kameyama, Yoshinori Kawabe, Akira Ito, Masamichi Kamihira

31. Improvement of CPP-RBD for siRNA Delivery
Rina Kuwabara, Tamaki Endoh, Masahiko Sisido, Takashi Ohtsuki

32. Production of Recombinant Human EPO and EPO/Fc Fusion Proteins by Chinese Hamster Ovary Cells
Carlos Alberto Penno, Yoshinori Kawabe, Akira Ito, Masamichi Kamihira

33. Development of Oviduct-Specific Gene Expression System for Transgenic Avian Bioreactor
Yoshinori Kawabe, Kensaku Numata, Masashi Teramori, Akira Ito, Masamichi Kamihira

34. Production of Therapeutic Proteins Composed of Seven Dominant Human T Cell Epitopes Derived from the Japanese Cedar Pollen Allergens
Yoshinori Kawabe, Yoshifumi Hayashida, Kensaku Numata, Akira Hishigae, Akira Ito, Masamichi Kamihira

35. The Differentiation of C2C12 Cells to Myotube by Paraquat
Masaaki Okabe, Koichi Akiyama, Sogo Nishimoto, Takuya Sugahara, Yoshimi Kakinuma

36. Molecular Cloning and Characterization of a Novel Canine Sulfotransferase
Katsuhisa Kurogi, Yoichi Sakakibara, Shin Yasuda, Ming-Cheh Liu, Masahito Suiko

37. In Vitro Analysis of the Interaction Between Human Intestinal Epithelial Cells and Macrophage-Like Cells
Yoko Ishimoto, Hideo Satsu, Tetsunosuke Mochizuki, Mamoru Totsuka, Makoto Shimizu

38. Role of Ubiquitination Promoted During Restimulation in the Induction of T Cell Anergy
Yohei Mizuguchi, Ai Yamamoto, Makoto Hattori, Tadashi Yoshida

39. Expression Analysis of Senescence-Associated Genes: Their Possible Involvement in Diabetes
Miyako Udono, Kaori Mukae, Tsukasa Fujiki, Zhang Ping Bo, Hiroshi Fujii, Sanetaka Shirahata, Yoshinori Katakura

40. Study of Butyrate Signal Transduction Pathways in Rat Hepatic Stem-Like Cells
Toshihiko Saheki, Yusuke Mukai, Ken’ichi Saito, Emi Tajima, Kentaro Katakura, Atsuyoshi Nishina, Mikiko Kishi, Takashi Izumi, Toshihiro Sugiyama, Itaru Kojima

41. Growth Control of Mammalian Cells via a Human Artificial Chromosome Harboring a Chimeric Receptor
Masahiro Kawahara, Toshiaki Inoue, Xianying Ren, Takahiro Sogo, Hidetoshi Yamada, Motonobu Katoh, Hiroshi Ueda, Mitsuo Oshimura, Teruyuki Nagamune

42. The Impact of Redox State on Regulation of the High-Affinity IgE Receptor Expression
Yoshinori Fujimura, Hayato Higo, Satomi Yano, Koji Yamada, Hirofumi Tachibana

43. The Characteristic of Chimeric Receptors Based on Erythropoietin Receptor
Wenhai Liu, Masahiro Kawahara, Hiroshi Ueda, Teruyuki Nagamune

44. Anti-Cancer and Structure-Activity Relationship of Natural Polyacetylenes
Soninkhishig Tsolmon, Yui Kurita, Si Won Hong, Parida Yamada, Hideyuki Shigemori, Hiroko Isoda

45. Effect of Mongolian Medicinal Plant Stellera Chamaejasme on Chronic Leukemia Cells K562
Soninkhishig Tsolmon, Parida Yamada, Hiroko Isoda

46. Capsaicin Induced the Upregulation of Transcriptional and Translational Expression of Glycolytic Enzymes Related to Energy Metabolism in Human Intestinal Epithelial Cells
Junkyu Han, Hiroko Isoda

47. Effect of Novel Compounds from Thymelaea Hirsuta on Melanogenesis
Myra O. Villareal, Yusaku Miyamae, Junkyu Han, Yamada Parida, Hideyuki Shigemori, Hiroko Isoda

48. Electrolyzed Reduced Water Prolongs Caenorhabditis elegans’ Lifespan
Hanxu Yan, Huaize Tian, Takeki Hamasaki, Masumi Abe, Noboru Nakamichi, Kiichiro Teruya, Yoshinori Katakura, Shinkatsu Morisawa, Sanetaka Shirahata

49. Anti-Cancer Effects of Enzyme-Digested Fucoidan Extract from Seaweed Mozuku
Yoshiko Matsuda, Kiichiro Teruya, Sakiko Matsuda, Ayumi Nakano, Takuya Nishimoto, Masashi Ueno, Akitomo Niho, Makiko Yamashita, Hiroshi Eto, Yoshinori Katakura, Sanetaka Shirahata

50. The Downregulation of Mast Cell Activation Through the Suppression of the High-Affinity IgE Receptor Expression by Green Tea Catechin Egcg
Hirofumi Tachibana, Yoshinori Fujimura, Yusuke Hasegawa, Satomi Yano, Koji Yamada

51. Anti-Diabetes Effects of Hita Tenryou-Sui Water
®
, a Natural Reduced Water
Kazuhiro Osada, Yuping Li, Takeki Hamasaki, Masumi Abe, Noboru Nakamichi, Kiichiro Teruya, Yoshitoki Ishii, Ying Wang, Yoshinori Katakura, Sanetaka Shirahata

52. Suppressive Effect of ERW on Lipid Peroxidation and Plasma Triglyceride Level
Masumi Abe, Shunpei Sato, Kazuko Toh, Takeki Hamasaki, Noboru Nakamichi, Kiichiro Teruya, Yoshinori Katakura, Shinkatsu Morisawa, Sanetaka Shirahata

53. Growth Suppression of HL60 and L6 Cells by Atomic Hydrogen

Kensuke Nakanishi, Takeki Hamasaki, Takuro Nakamura, Masumi Abe, Kiichiro Teruya, Yoshinori Katakura, Shinkatsu Morisawa, Sanetaka Shirahata

54. Insulin-Mimetic Activity of Inositol Derivatives Depends on Phosphorylation of PKCζ/λ in L6 Myotubes
Nhung Thuy Dang, Masanori Yamaguchi, Tadashi Yoshida, Ken-ichi Yoshida, Hitoshi Ashida

55. Enhancement of Phagocytic Activity by a Crude Polysaccharide from Tea (Camellia sinensis) Extract
Manami Monobe, Kaori Ema, Keiko Azuma, Mari Maeda-Yamamoto

56. Effects of Lupeol on Melanoma In Vitro and In Vivo: Fundamental and Clinical Trials
Keishi Hata, Kikumi Ogihara, Saori Takahashi, Takeshi Tsuka, Saburo Minami, Yoshiharu Okamoto

57. The Effect of Secoisolariciresinol on 3t3-L1 Adipocytes and the Relationship Between Molecular Structure and the Activity
Shiori Tominaga, Takuya Sugahara, Sogo Nishimoto, Manami Yamawaki, Yuki Nakashima, Taro Kishida, Koichi Akiyama, Masafumi Maruyama, Satoshi Yamauchi

58. Detection of Anti-Allergic Factors in Strawberry Extracts
Kazuhiro Mitsuda, Aiko Inoue, Norikazu Nishino, Yuichi Inoue, Hiroharu Kawahara

59. Anti-Melanogenic Activity of Yacon Leaves in Mouse Melanoma Cells
Tomoyuki Ishikawa, Toshio Hyakutake, Yasuaki Gondou, Mitsuhiro Sakai, Reiko Kinoshita, Jyunji Tottori, Hiroshi Kunitake, Ken-Ichi Kusumoto

60. Cytokine Responses of Splenocytes of Female and Male Non-Obese Diabetic Mice Induced by Lactic Acid Bacteria
Atsushi Enomoto, Mohd Azraai Bin Jamal, Hiromi Mitsui, Hiromi Kimoto-Nira, Chise Suzuki, Koko Mizumachi

61. Development of a High-Throughput Evaluation System for Antiviral Activities of Food Factors By Using Bioinformatics
Nozomu Eto, Kiyoko Nagahama, Shohei Miyamoto, Osayoshi Yamaguchi, Sayumi Miyauchi, Takako Iwata, Asuka Uchida, Kunihito Yamamori

62. The Effects of Pesticides on Immune Cells
Sogo Nishimoto, Kota Kanda, Masaaki Okabe, Koichi Akiyama, Yoshimi Kakinuma, Takuya Sugahara

63. Co-Cultured Hepatocyte-Spheroid Chip Constructed Using the Microfabrication Technique
Yusuke Sakai, Kohji Nakazawa

64. Micropatterned Hepatocyte Culture Using Microstencil Technique
Yukako Shinmura, Ami Higuchi, Yusuke Sakai, Kohji Nakazawa

65. Structural Features of Totally Designed Lipidic Materials for Small Interfering RNA Delivery System
Ken-Ichi Kusumoto

66.
Thin-Film Assembly of Totally Designed Lipidic Materials as Gene Carrier in Mouse Embryonic Neural Stem Cells: Thin-Film Assembly of Lipidic Material as Potential Gene Carrier
Ken-Ichi Kusumoto, Takahiro Nagata, Itaru Hamachi

67.
Transfection System Using a Cocktail of Totally Designed Lipidic Materials in Chinese Hamster Ovary Cells: Lipidic Cocktail as Potential Gene Carrier for CHO Cells
Ken-Ichi Kusumoto, Takahiro Nagata, Eiichi Kanazawal, Takanori Sakai, Yoshihiko Yoshikawa, Takahiro Ogata, Naomi Nakatani, Tomoyuki Ishikawa, Shintaro Koga, Akio Shirasu, Shinji Morishita, Takayuki Emura, Itaru Hamachi

68. Size Dependent Heat Generation of Magnetic Nanoparticles Under AC Magnetic Field for Cancer Therapy
Jun Motoyama, Toshiyuki Hakata, Ryuji Kato, Noriyuki Yamashita, Tomio Morino, Takeshi Kobayashi, Hiroyuki Honda

69. Functional Evaluation of Anticancer Drugs in Human Leukemia Cells Based on Metabolic Profiling Technique
Daisuke Miura, Yoshinori Fujimura, Hirofumi Tachibana, Hiroyuki Wariishi

70. Extracts from the Root of Platycodon grandiflorum Modulate Induction of Inflammatory Changes in Coculture of Adipocytes and Macrophages
Ju-Hye Lee, Koji Yamada, Hirofumi Tachibana

71. Position Specific Incorporation of Nonnatural Amino Acids into Proteins In Vivo
Satoshi Neki, Takashi Ohtsuki, Masahiko Sisido

72. Novel Protease Inhibitor Inhibiting Proliferation of Influenza Virus: Purification and cDNA Cloning of a Novel Protease Inhibitor Secreted by MDCK Cells
Kiyoto Nishiyama, Keishin Sugawara, Kenji Soejima, Shin-ichi Abe, Hiroshi Mizokami

Nyckelord: Biomedicine, Biomedicine general, Cell Biology, Life Sciences, general, Biotechnology, Food Science