The Comparative Biology of Aging

1. Introduction: Lifespans and Pathologies Present at Death in Laboratory Animals
Norman S. Wolf, Steven Austad

2. Animal Size, Metabolic Rate, and Survival, Among and Within Species
Steven N. Austad

3. Hormonal Influences on Aging and Lifespan
Adam Spong, Andrzej Bartke

4. Exploring Mechanisms of Aging Retardation by Caloric Restriction: Studies in Model Organisms and Mammals
Rozalyn M. Anderson, Ricki J. Colman, Richard Weindruch

5. Cell Replication Rates In Vivo and In Vitro and Wound Healing as Affected by Animal Age, Diet, and Species
Norman S. Wolf

6. Sirtuin Function in Longevity
Daniel L. Smith Jr., Jeffrey S. Smith

7. The Role of TOR Signaling in Aging
Matt Kaeberlein, Lara S. Shamieh

8. Mitochondria, Oxidative Damage and Longevity: What Can Comparative Biology Teach Us?
Yun Shi, Rochelle Buffenstein, Holly Remmen

9. Comparative Genomics of Aging
Jan Vijg, Ana Maria Garcia, Brent Calder, Martijn Dollé

10. Changes in Lysosomes and Their Autophagic Function in Aging: The Comparative Biology of Lysosomal Function
Samantha J. Orenstein, Ana Maria Cuervo

11. Telomeres and Telomerase
N.M.V. Gomes, J.W. Shay, W. E. Wright

12. Cardiac Aging
Dao-Fu Dai, Robert J. Wessells, Rolf Bodmer, Peter S. Rabinovitch

13. Comparative Skeletal Muscle Aging
David J. Marcinek, Jonathan Wanagat, Jason J. Villarin

14. Aging of the Nervous System
Catherine A. Wolkow, Sige Zou, Mark P. Mattson

15. Aging of the Immune System Across Different Species
Janko Nikolich-Žugich, Luka Čičin-Šain

Nyckelord: Biomedicine, Biomedicine general, Geriatrics/Gerontology, Oxidative Stress, Cell Physiology