Molecular Science of Fluctuations Toward Biological Functions

1. Time-Resolved Detection of Protein Fluctuations During Reactions
Masahide Terazima

2. Pressure Perturbation: A Prime Tool to Study Conformational Substates and Volume Fluctuations of Biomolecular Assemblies
Shobhna Kapoor, Roland Winter

3. Watching a Signaling Protein Function in Real Time via Picosecond Time-Resolved Laue Crystallography
Friedrich Schotte, Hyun Sun Cho, Hironari Kamikubo, Mikio Kataoka, Philip A. Anfinrud

4. NMR Explorations of Biomolecular Systems with Rapid Conformational Exchanges
Maho Yagi-Utsumi, Takumi Yamaguchi, Ryo Kitahara, Koichi Kato

5. Site-Specific Incorporation of Fluorescent Nonnatural Amino Acids into Proteins and Its Application to Fluorescence Analysis of Proteins
Takahiro Hohsaka

6. Unfoldomes and Unfoldomics: Introducing Intrinsically Disordered Proteins
Bin Xue, Vladimir N. Uversky

7. Structure, Dynamics, and Function of Staphylococcal Nuclease
Mikio Kataoka

8. Theory of Molecular Recognition and Structural Fluctuation of Biomolecules
Fumio Hirata, Norio Yoshida, Bongsoo Kim

9. Structural Fluctuations of Proteins in Folding and Ligand Docking Studied by Replica-Exchange Simulations
Yuko Okamoto

10. Spatiotemporal Fluctuations of Protein Folding in Living Cells
Minghao Guo, Martin Gruebele

11. Membrane-Targeted Nanotherapy with Hybrid Liposomes for Cancer Cells Leading to Apoptosis
Ryuichi Ueoka, Yoko Matsumoto, Hideaki Ichihara, Yuji Komizu

12. Antitumor Complexes Formed by Oleic Acid and Molten Globule Intermediates of Proteins
Kunihiro Kuwajima, Takashi Nakamura

Nyckelord: Chemistry, Bioorganic Chemistry, Protein-Ligand Interactions, Biophysics and Biological Physics, Physical Chemistry, Computer Appl. in Life Sciences, Molecular Medicine