Osteosarcoma

Part I. Basic Research and Experimental Therapy

1. Genetics of Osteosarcoma
Junya Toguchida

2. Basic Research for Osteosarcoma Lung Metastasis (LM8)
Kazuyuki Itoh

3. Immunotherapy for Osteosarcoma
Tomohide Tsukahara, Takuro Wada

Part II. Clinical Features

4. Outcome of Treatment for Osteosarcoma of the Extremities Over the Last 20 Years: Report from 11 Referral Centers in Japan
Koichi Ogura, Hiroaki Hiraga, Takeshi Ishii, Toshifumi Ozaki, Yoshihiro Nishida, Hideo Morioka, Toru Hiruma, Takafumi Ueda, Nobuhito Araki, Norifumi Naka, Hirotaka Kawano, Akira Kawai

5. Osteosarcoma in the Elderly: Clinical Features and Outcome
Yoshihiro Nishida

6. Prognostic Factors for Osteosarcoma Patients
Mitsunori Kaya

Part III. Chemotherapy

7. Neoadjuvant Chemotherapy Developed in Japan
Hiroaki Hiraga

8. Neoadjuvant Chemotherapy: Osaka University Osteosarcoma (OOS) Regimen
Shigeki Kakunaga, Takafumi Ueda, Norifumi Naka, Shigeyuki Kuratsu, Nobuhito Araki, Yasuaki Aoki, Hideki Yoshikawa

Part IV. Surgery

9. Endoprosthetic Reconstruction for Extremity Osteosarcoma
Akihiko Matsumine

10. Limb-Salvage Surgery and Reconstruction for Skeletally Immature Childhood Osteosarcoma: Extendible Endoprosthesis
Hiroyuki Futani, Shinichi Yoshiya

11. Limb Salvage Surgery for Pelvic Osteosarcoma
Toshiyuki Kunisada, Ken Takeda, Tomohiro Fujiwara, Shinsuke Sugihara, Toshifumi Ozaki

12. Management of Postoperative Infection After Limb Salvage Surgery in Osteosarcoma Patients
Takeshi Morii

Part V. Surgery: Biological Reconstruction

13. Biological Reconstruction for Extremity Osteosarcoma: Long-Term Results and Current Concept of Intraoperative Extracorporeal Irradiated Bone Graft (IORBG)
Nobuhito Araki

14. Biological Reconstruction for Extremity Osteosarcoma: Pasteurized Autogenous Bone Graft
Keisuke Ae

15. Biological Reconstruction for Extremity Osteosarcoma: Liquid Nitrogen-Treated Tumor-Bearing Bone Graft
Hiroyuki Tsuchiya, Norio Yamamoto

16. Biological Reconstruction for Extremity Osteosarcoma: Distraction Osteogenesis Technique
Hidenori Matsubara, Hiroyuki Tsuchiya

17. Limb-Saving Surgery Using In Situ Preparation (ISP) Method
Seiichi Matsumoto, Keisuke Ae

Part VI. Unresectable/Metastatic Disease

18. Carbon Ion Radiotherapy for Unresectable Osteosarcoma of the Trunk
Reiko Imai, Tadashi Kamada

19. Treatment of Osteosarcoma Patients with Pulmonary Metastasis
Shintaro Iwata, Tsukasa Yonemoto, Hiroto Kamoda, Takeshi Ishii

Part VII. Quality of Life

20. Long-Term Outcomes and Quality of Life (QOL) in Survivors of Pediatric and Adolescent Osteosarcoma
Tsukasa Yonemoto, Shintaro Iwata, Hiroto Kamoda, Takeshi Ishii

Nyckelord: Medicine & Public Health, Surgical Oncology, Orthopedics, Radiotherapy