Erythropoietins, Erythropoietic Factors, and Erythropoiesis

1. Erythropoiesis: an overview
Bruce E. Torbett, Jeffrey S. Friedman

2. Regulation of endogenous erythropoietin production
David R. Mole, Peter J. Ratcliffe

3. Biology of erythropoietin
Graham Molineux, Angus M. Sinclair

4. Erythropoiesis—genetic abnormalities
Josef T. Prchal, Xylina T. Gregg

5. Studies of erythropoiesis and the discovery and cloning of recombinant human erythropoietin
Mary Ann Foote

6. Commercial production of recombinant erythropoietins
Alice S. Chuck, Adrian Distler, Shane A. Sander, Rohini R. Deshpande, Gregg Nyberg, James E. Seely

7. Biosimilar epoetins
Huub Schellekens

8. New molecules and formulations
Steven G. Elliott

9. Structural basis for the signal transduction of erythropoietin
Timothy D. Osslund

10. Intracellular signaling by the erythropoietin receptor
Harvey F. Lodish, Saghi Ghaffari, Merav Socolovsky, Wei Tong, Jing Zhang

11. Mechanism of erythropoietin receptor activation
Stefan N. Constantinescu

12. Pharmacokinetics of erythropoiesis-stimulating agents
Sameer Doshi, Juan Jose Perez-Ruixo, Graham R. Jang, Andrew T. Chow

13. Use of erythropoietic stimulating agents in the setting of renal disease
David A. Goodkin

14. Abuse of recombinant erythropoietins and blood products by athletes
Don H. Catlin, Caroline K. Hatton

15. Role and regulation of iron metabolism in erythropoiesis and disease
Tara L. Arvedson, Barbra J. Sasu

16. Nonhematopoietic effects of erythropoiesis-stimulating agents
Wolfgang Jelkmann, Reinhard Depping, Eric Metzen

Nyckelord: Biomedicine, Pharmacology/Toxicology, Cell Biology, Sports Medicine, Endocrinology