Antimicrobials

Part I. Current Trends in Antibiotics, Pathogens and Medical Needs

1. The Origin and Evolution of Antibiotics
Julian Davies

2. Novel Infectious Diseases and Emerging Gram-Positive Multi-Resistant Pathogens in Hospital and Community Acquired Infections
Gian Maria Rossolini, Fabio Arena, Simona Pollini

3. Gram-Negative Pathogens: Overview of Novel and Emerging Resistant Pathogens and Drugs
Yossi Paitan, Eliora Z. Ron

Part II. Families of Novel Candidates and Conventional Antibiotics

4. The β-Lactam Antibiotics: Their Future in the Face of Resistance
Erika Leemans, Jed F. Fisher, Shahriar Mobashery

5. Glycopeptides: An Old but Up-to-Date Successful Antibiotic Class
Giorgia Letizia Marcone, Flavia Marinelli

6. Daptomycin and Related Lipopeptides Produced by Fermentation, Chemical Modification, and Combinatorial Biosynthesis
Richard H. Baltz

7. Lantibiotics and Similar Peptides Produced by and Active on Gram-Positives: Discovery, Development and Perspectives
Jesus Cortes

8. Old and Novel Polymyxins Against Serious Gram-Negative Infections
Martti Vaara

9. Uridyl Peptide Antibiotics: Developments in Biosynthesis and Medicinal Chemistry
Guy T. Carter, Leonard A. McDonald

10. Aminoglycoside Antibiotics
Herbert A. Kirst, Flavia Marinelli

11. Macrolide Antibiotics
Herbert A. Kirst

12. Tetracycline Antibiotics and Novel Analogs
Olga Genilloud, Francisca Vicente

13. Oxazolidin-2-Ones: Antibacterial Activity and Chemistry
Giovanni Zappia, Cinzia Ingallina, Francesca Ghirga, Bruno Botta

14. Protein Synthesis Inhibitors from Smaller Antibiotic Classes
Herbert A. Kirst

15. Actinonin and Analogs: Inhibitors of Bacterial Peptide Deformylase
Stephen P. East

16. Bacterial Topoisomerase Inhibitors: Quinolones and Beyond
Michael J. Pucci, Jason A. Wiles

17. Strategies to Discover Novel Antimicrobials to Cope with Emerging Medical Needs
Olga Genilloud, Francisca Vicente

Nyckelord: Biomedicine, Medical Microbiology, Drug Resistance, Infectious Diseases, Applied Microbiology