Dupuytren’s Disease and Related Hyperproliferative Disorders

1. Dupuytren’s Disease: Anatomy, Pathology, and Presentation
Ghazi M. Rayan

2. Palmar Fibromatosis or the Loss of Flexibility of the Palmar Finger Tissue: A New Insight into the Disease Process of Dupuytren Contracture
Albrecht Meinel

3. Basic Thoughts on Dupuytren’s Contracture
Hanno Millesi

4. High Prevalence of Dupuytren’s Disease and Its Treatment in the British National Health Service: An Ongoing Demand
Karen Zaman, Sandip Hindocha, Ardeshir Bayat

5. Treatment for Dupuytren’s Disease: An Overview of Options
Annet L. Rijssen, Paul M. N. Werker

6. Dupuytren’s Disease and Occupation
Alexis Descatha

7. The Role of the Myofibroblast in Dupuytren’s Disease: Fundamental Aspects of Contraction and Therapeutic Perspectives
Boris Hinz, Giulio Gabbiani

8. Mechanisms of Myofibroblast Differentiation
Sem H. Phan

9. Myofibroblasts and Interactions with Other Cells: Contribution of the Tissue Engineering
Véronique Moulin, Judith Bellemare, Daniele Bergeron, Herve Genest, Michel Roy, Carlos Lopez-Vallé

10. Dupuytren’s Contracture Versus Burn Scar Contracture
Paul Zidel

11. The Genetic Basis of Dupuytren’s Disease: An Introduction
Guido H. C. G. Dolmans, Hans C. Hennies

12. Use of Genetic and Genomic Analyses Tools to Study Dupuytren’s Disease
Barbara Shih, Stewart Watson, Ardeshir Bayat

13. Establishing an Animal Model of Dupuytren’s Contracture by Profiling Genes Associated with Fibrosis
Latha Satish, Mark E. Baratz, Bradley Palmer, Sandra Johnson, J. Christopher Post, Garth D. Ehrlich, Sandeep Kathju

14. Microarray Expression Analysis of Primary Dupuytren’s Contracture Cells
Sandra Kraljevic Pavelic, Ivana Ratkaj

15. A Clinical Genetic Study of Familial Dupuytren’s Disease in the Netherlands
Guido H. C. G. Dolmans, Cisca Wijmenga, Roel Ophoff, Paul M. N. Werker

16. The Epidemiology of Dupuytren’s Disease in Bosnia
Dragan Zerajic, Vilhjalmur Finsen

17. A Primer of Collagen Biology: Synthesis, Degradation, Subtypes, and Role in Dupuytren’s Disease
Susan Emeigh Hart

18. The Expression of Collagen-Degrading Proteases Involved in Dupuytren’s Disease Fibroblast-Mediated Contraction
Janine M. Wilkinson, Eleanor R. Jones, Graham P. Riley, Adrian J. Chojnowski, Ian M. Clark

19. Primary Dupuytren’s Disease Cell Interactions with the Extra-cellular Environment: A Link to Disease Progression?
Linda Vi, Yan Wu, Bing Siang Gan, David B. O’Gorman

20. Insulin-Like Growth Factor Binding Protein-6: A Potential Mediator of Myofibroblast Differentiation in Dupuytren’s Disease?
Christina Raykha, Justin Crawford, Bing Siang Gan, David B. O’Gorman

21. Dupuytren’s Disease Shows Populations of Hematopoietic and Mesenchymal Stem-Like Cells Involving Perinodular Fat and Skin in Addition to Diseased Fascia: Implications for Pathogenesis and Therapy
Syed Amir Iqbal, Sandip Hindocha, Syed Farhatullah, Ralf Paus, Ardeshir Bayat

22. Using Laboratory Models to Develop Molecular Mechanistic Treatments for Dupuytren’s Disease
Martin C. Robson, Wyatt G. Payne

23. Plastic Surgical Management of Scars and Soft Tissue Contractures
Paul M. N. Werker

24. Cline’s Contracture: Dupuytren Was a Thief – A History of Surgery for Dupuytren’s Contracture
A. Lee Osterman, Peter M. Murray, Teresa J. Pianta

25. Cellulose Implants in Dupuytren’s Surgery
Ilse Degreef, Luc Smet

26. Expanded Dermofasciectomies and Full-Thickness Grafts in the Treatment of Dupuytren’s Contracture: A 36-Year Experience
Lynn D. Ketchum

27. Minimizing Skin Necrosis and Delayed Healing After Surgical Treatment for Dupuytren’s Contracture: The Mini-Chevrons Incision
Michael Papaloïzos

28. Skin Management in Treatment of Severe PIP Contracture by Homo- or Heterodigital Flaps
Bernhard Lukas, Moritz Lukas

29. The “Jacobsen Flap” for the Treatment of Stage III–IV Dupuytren’s Disease at Little Finger: Our Review of 123 Cases
Massimiliano Tripoli, Francesco Moschella, Michel Merle

30. A Logical Approach to Release of the Contracted Proximal Interphalangeal Joint in Dupuytren’s Disease
Paul Smith

31. The Influence of Dupuytren’s Disease on Trigger Fingers and Vice Versa
Bernd Kuehlein

32. No Higher Self-Reported Recurrence in Segmental Fasciectomy
Ilse Degreef

33. Palmar Cutaneous Branches of the Proper Digital Nerves Encountered in Dupuytren’s Surgery: A Cadaveric Study
Robert M. Choa, Andrew F. M. McKee, Ian S. H. McNab

34. A Technique of Needle Aponeurotomy for Dupuytren’s Contracture
Charles Eaton

35. Three-Year Results of First-Ever Randomized Clinical Trial on Treatment in Dupuytren’s Disease: Percutaneous Needle Fasciotomy Versus Limited Fasciectomy
Annet L. Rijssen, Hein Linden, Paul M. N. Werker

36. Management of Dupuytren’s Disease with Needle Aponeurotomy: The Experience at the Hand and Upper Limb Centre, Canada
Aaron Grant, David B. O’Gorman, Bing Siang Gan

37. Percutaneous Needle Fasciotomy: A Serious Alternative?
Holger C. Erne, Ahmed El Gammal, Bernhard Lukas

38. Dynamic External Fixation in the Treatment of Dupuytren’s Contracture
George A. Lawson, Anthony A. Smith

39. Hand Therapy for Dupuytren’s Contracture
Patricia Davis, Charles Eaton

40. Severity of Contracture and Self-Reported Disability in Patients with Dupuytren’s Contracture Referred for Surgery
Christina Jerosch-Herold, Lee Shepstone, Adrian J. Chojnowski, Debbie Larson

41. Night-Time Splinting After Fasciectomy or Dermofasciectomy for Dupuytren’s Contracture: A Pragmatic, Multi-centre, Randomised Controlled Trial
Christina Jerosch-Herold, Lee Shepstone, Adrian J. Chojnowski, Debbie Larson, Elisabeth Barrett, Susan P. Vaughan

42. The Role of Static Night Splinting After Contracture Release for Dupuytren’s Disease: A Preliminary Recommendation Based on Clinical Cases
Albrecht Meinel

43. Injectable Collagenase (Clostridium histolyticum) for Dupuytren’s Contracture: Results of the CORD I Study
Marie A. Badalamente

44. Long-Term Outcome of Radiotherapy for Early Stage Dupuytren’s Disease: A Phase III Clinical Study
Michael Heinrich Seegenschmiedt, Ludwig Keilholz, Mark Wielpütz, Christine Schubert, Fabian Fehlauer

45. Outcomes of Using Bioengineered Skin Substitute (Apligraf®) for Wound Coverage in Dupuytren’s Surgery
E. Anne Ouellette, Melissa Diamond, Anna-Lena Makowski

46. Highly Dosed Tamoxifen in Therapy-Resisting Dupuytren’s Disease
Ilse Degreef, Sabine Tejpar, Luc Smet

47. Screening of Prodrugs on Cells Grown from Dupuytren’s Disease Patients
Davor Jurisic

48. Relaxin: An Emerging Therapy for Fibroproliferative Disorders
Chrishan S. Samuel

49. Cryotherapy and Other Therapeutical Options for Plantar Fibromatosis
Terry L. Spilken

50. Long-Term Outcome of Radiotherapy for Primary and Recurrent Ledderhose Disease
Michael Heinrich Seegenschmiedt, Mark Wielpütz, Etienne Hanslian, Fabian Fehlauer

51. Medical Management of Peyronie’s Disease
Ma Limin, Aaron Bernie, Wayne J. G. Hellstrom

52. The Patient’s Perspective and the International Dupuytren Society
Wolfgang Wach

53. IDUP: Proposal for an International Research Database
Charles Eaton, Michael Heinrich Seegenschmiedt, Wolfgang Wach

54. The Future of Dupuytren’s Research and Treatment
Charles Eaton

Nyckelord: Medicine & Public Health, Orthopedics, Surgical Orthopedics, General Practice / Family Medicine, Dermatology