Pediatric Clinical Pharmacology

1. Basics and Dynamics of Neonatal and Pediatric Pharmacology
Hannsjörg W. Seyberth, Ralph E. Kauffman

2. Developmental Pharmacokinetics
Johannes N. Anker, Matthias Schwab, Gregory L. Kearns

3. Principles of Therapeutic Drug Monitoring
Wei Zhao, Evelyne Jacqz-Aigrain

4. Drug Delivery and Formulations
Jörg Breitkreutz, Joachim Boos

5. Development of Paediatric Medicines: Concepts and Principles
Klaus Rose, Oscar Della Pasqua

6. Study Design and Simulation Approach
Stephanie Läer, Bernd Meibohm

7. Efficacy Assessment in Paediatric Studies
Siri Wang, Pirjo Laitinen-Parkkonen

8. Safety Assessment in Pediatric Studies
Gideon Koren, Abdelbasset Elzagallaai, Fatma Etwel

9. Small Sample Approach, and Statistical and Epidemiological Aspects
Martin Offringa, Hanneke Lee

10. Sample Collection, Biobanking, and Analysis
Maurice J. Ahsman, Dick Tibboel, Ron A. A. Mathot, Saskia N. Wildt

11. Ethical Considerations in Conducting Pediatric Research
Michelle Roth-Cline, Jason Gerson, Patricia Bright, Catherine S. Lee, Robert M. Nelson

12. Pediatric Regulatory Initiatives
Steven Hirschfeld, Agnes Saint-Raymond

13. Fetal Medicine and Treatment
Magnus Westgren

14. Fetal Risks of Maternal Pharmacotherapy: Identifying Signals
Gideon Koren

15. Antiepileptic Treatment in Pregnant Women: Morphological and Behavioural Effects
Torbjörn Tomson, Dina Battino

16. Preventive Medicines
Ulrich Heininger

17. Postmarketing Surveillance
Vera Vlahović-Palčevski, Dirk Mentzer

18. Global Aspects of Drug Development
Kalle Hoppu, Hans V. Hogerzeil

Nyckelord: Biomedicine, Pharmacology/Toxicology, Pediatrics, Laboratory Medicine