Resistance to Anti-Cancer Therapeutics Targeting Receptor Tyrosine Kinases and Downstream Pathways

1. Resistance of Colorectal Tumors to Anti-EGFR Antibodies
Livio Trusolino, Simonetta M. Leto

2. Resistance of Lung Cancer to Kinase Inhibitors Specific to EGFR or ALK
Maicol Mancini, Yosef Yarden

3. Mechanisms of Action and Resistance of Trastuzumab in Breast Cancer
Jennifer L. Hsu, Mien-Chie Hung

4. Mechanisms of Resistance to Molecular Therapies Targeting the HGF/MET Axis
Simona Corso, Silvia Giordano

5. RAF, MEK and ERK Inhibitors as Anti-Cancer Drugs: Intrinsic and Acquired Resistance as a Major Therapeutic Challenge
Galia Maik-Rachline, Izel Cohen, Rony Seger

6. Mechanisms of Resistance to PI3K and AKT Inhibitors
Pau Castel, Maurizio Scaltriti

7. Sensitivity and Resistance to BH3 Mimetics in Cancer Therapy
Konstantinos V. Floros, Anthony C. Faber, Hisashi Harada

8. Resistance Mechanisms to Cyclin-Dependent Kinase Inhibitors
Wolf Ruprecht Wiedemeyer

9. Resistance to Inhibitors of Angiogenesis
Nili Dahan, Ksenia Magidey, Yuval Shaked

Nyckelord: Biomedicine, Cancer Research