Pre-Menopause, Menopause and Beyond

Part I. Menopause: Symptoms and Neuroendocrine Impact

1. Intracrinology: The New Science of Sex Steroid Physiology in Women
Fernand Labrie

2. From Menopause to Aging: Endocrine and Neuroendocrine Biological Changes
Alessandro D. Genazzani, Andrea Giannini, Antonella Napolitano

3. Brain Impact of Sex Steroid Withdrawal at Menopause
Nicola Pluchino, Andrea R. Genazzani

4. Climacteric Symptoms: Importance and Management
Martin Birkhaeuser

Part II. Fertility

5. Progress in Recommendations on Menopause, MHT and POI
Nick Panay

6. Female Infertility and Autoimmunity
Paolo Giovanni Artini, Patrizia Monteleone

Part III. Thyroid Disorders, Polycystic Ovary and Metabolic Syndrome

7. Oocyte Donation in Perimenopausal and Menopausal Women
Basil Tarlatzis, Julia Bosdou

8. Thyroid Disorders in Climacteric Women
Anna Brona, Andrzej Milewicz, Justyna Kuliczkowska-Płaksej, Marek Bolanowski

9. Thyroid Function and Pregnancy Outcome After ART: What Is the Evidence?
Gesthimani Mintziori, Dimitrios G. Goulis, Basil C. Tarlatzis

10. PCOS: Implications of Cardiometabolic Dysfunction
Bart C. J. M. Fauser

11. Why Metformin Is so Important for Prevention and Therapy in Climacteric Women
Justyna Kuliczkowska-Plaksej, Andrzej Milewicz, Anna Brona, Marek Bolanowski

12. Metabolic Changes and Metabolic Syndrome During the Menopausal Transition
Alessandro D. Genazzani, Alessia Prati, Giulia Despini

13. Weight and Body Composition Management After Menopause: The Effect of Lifestyle Modifications
Irene Lambrinoudaki, Eleni Armeni, Nikolaos Tsoltos

Part IV. Bone and Cardiovascular Impact

14. Healthy Bones After Menopause: What Has to Be Done?
Martin Birkhaeuser

15. The Effect of Menopause and HRT on Coronary Heart Disease
John C. Stevenson

16. How to Prevent Cardiovascular Disorders: Influence of Gonadal Steroids on the Heart
Svetlana Vujovic, Milina Tancic-Gajic, Ljiljana Marina, Zorana Arizanovic, Zorana Stojanovic, Branko Barac, Aleksandar Djogo, Miomira Ivovic

Part V. Benign Breast Diseases, BRCA Mutation and Breast Cancer

17. Risk-Reducing Surgery and Treatment of Menopausal Symptoms in BRCA Mutation Carriers (and Other Risk Women)
Piero Sismondi, Marta D’Alonzo, Paola Modaffari, Viola Liberale, Valentina Elisabetta Bounous, Andrea Villasco, Nicoletta Biglia

18. Benign Breast Disease During Women’s Life
Svetlana Vujovic

19. Treatment of Menopausal Symptoms in Breast Cancer Survivors
Piero Sismondi, Valentina Elisabetta Bounous, Valentina Tuninetti, Viola Liberale, Martina Gallo, Nicoletta Biglia

20. Myoinositol and Inositol Hexakisphosphate in the Treatment of Breast Cancer: Molecular Mechanisms
Mariano Bizzarri, Simona Dinicola, Alessandra Cucina

Part VI. Menopause Symptoms: The Therapies

21. The True Risks of HRT
John C. Stevenson

22. Menopause Hormone Therapy Customization
Irene Lambrinoudaki, Eleni Armeni

23. GSM/VVA: Advances in Understanding and Management
Nick Panay

24. Intravaginal DHEA for the Treatment of Vulvovaginal Atrophy, Intracrinology at Work
Fernand Labrie

Part VII. Surgical Challenges After Menopause: Problems and Solutions

25. Bladder Dysfunction and Urinary Incontinence After the Menopause: Hormones, Drugs, or Surgery?
Eleonora Russo, Andrea Giannini, Marta Caretto, Paolo Mannella, Tommaso Simoncini

26. When is Tubectomy and When Ovarectomy/Adnexectomy Indicated at Necessary Hysterectomies Beyond the Reproductive Age?
Liselotte Mettler

27. Pelvic Floor Reconstructive Surgery in Ageing Women: Tailoring the Treatment to Each Woman’s Needs
Marta Caretto, Andrea Giannini, Eleonora Russo, Paolo Mannella, Tommaso Simoncini

Nyckelord: Medicine & Public Health, Gynecology, Endocrinology, Reproductive Medicine