Patient-Derived Xenograft Models of Human Cancer

1. Patient-Derived Tumor Xenografts: Historical Background
Dong Lin, Xinya Wang, Peter W. Gout, Yuzhuo Wang

2. Towards Best Practice in Establishing Patient-Derived Xenografts
Gail P. Risbridger, Mitchell G. Lawrence

3. Fidelity and Stability of PDX Models
Gang Li

4. Humanized Mouse and Rat PDX Cancer Models
Fallon K. Noto, Tseten Yeshi

5. Studies of Cancer Heterogeneity Using PDX Models
Danyi Wen, Feifei Zhang, Yuan Long

6. The Plasticity of Stem-Like States in Patient-Derived Tumor Xenografts
Alastair H. Davies, Fraser Johnson, Kirsi Ketola, Amina Zoubeidi

7. Modeling Cancer Metastasis
Nora M. Navone, Estefania Labanca

8. Modeling Drug Resistance in PDX Models
Erin L. Stewart, Ming Sound Tsao

9. Using PDX for Biomarker Development
Werner J. Struss, Peter C. Black

10. Patient-Derived Xenografts as Cancer Models for Preclinical Drug Screening
Juliet A. Williams

11. First-Generation Tumor Xenografts: A Link Between Patient-Derived Xenograft Models and Clinical Disease
Xin Dong, Peter W. Gout, Lu Yi, Yinhuai Wang, Yong Xu, Kuo Yang

12. Application of PDX Cancer Models in Co-clinical Trials and Personalized/Precision Medicine
Hongwei Cheng, Zongwen Liu, Hui Xue, Peter W. Gout, Hong Shan

13. Prospectives
Dong Lin, Yuzhuo Wang, Peter W. Gout

Nyckelord: Medicine & Public Health, Oncology