Malignant Brain Tumors

Part I. Molecular and Clinical Characterization of Gliomas

1. Use of Advanced Neuroimaging (fMRI, DTI/Tractography) in the Treatment of Malignant Gliomas
Nicole M. Petrovich Brennan, Andrei I. Holodny

2. Molecular Neuropathology and the Ontogeny of Malignant Gliomas
Anita Huttner

3. Personalized Medicine Through Advanced Genomics
Mark W. Youngblood, E. Zeynep Erson-Omay, Murat Günel

Part II. Surgery: Maximizing the Extent of Tumor Resection

4. The Usefulness of Stereotactic Neuronavigation Along with Intraoperative Imaging in Malignant Brain Tumor Surgery
Gregory Kuzmik, Anne Long, S. Bulent Omay, Jennifer Moliterno Günel

5. Mapping the Brain for Primary Brain Tumor Surgery
Emmanuel Mandonnet, Hugues Duffau

6. Fluorescence-Guided Resection of Malignant Gliomas
Walter Stummer

7. The Role of Laser-Induced Thermal Therapy in the Management of Malignant Gliomas
Elena Fomchenko, Veronica L. S. Chiang

Part III. Adjuvant Therapies

8. Current Standard Treatment Options for Malignant Glioma
Kevin P. Becker, Joachim M. Baehring

9. Targeting Aberrant Signaling Pathways
Jacob Mandel, Santosh Kesari

10. Targeted Therapy of IDH1-Mutated Tumors
Owen Clark, Christian Grommes

11. Antiangiogenic Therapy for Malignant Gliomas
Nancy Wang, Jonas Kloepper, Rakesh K. Jain, Tracy T. Batchelor

12. Immunotherapy for High-Grade Gliomas
Teilo H. Schaller, John H. Sampson

13. Novel Delivery Strategies
David S. Hersh, Aniket S. Wadajkar, Graeme F. Woodworth

14. Radiation Therapy for Malignant Gliomas: Current Options
Laura E. G. Warren, Marc R. Bussiére, Helen A. Shih

15. Glioma Radiosensitizers: Exciting New Developments and Directions
Christopher D. Corso, Ranjit S. Bindra

Part IV. Tumor-Specific Approach

16. Infiltrative Glioma
Ghazaleh Tabatabai

17. Tumor-Specific Approach: Oligodendroglioma (IDH1 Mutated, 1p/19q Deleted)
Charles Marc Leyrer, Erin Murphy, Manmeet Ahluwalia

18. Glioblastoma
Hans-Georg Wirsching, Michael Weller

Nyckelord: Medicine & Public Health, Neurosurgery, Surgical Oncology