Immunotherapy of Melanoma

Part I. Melanoma

1. Melanoma—Introduction, History and Epidemiology
Anand Rotte, Madhuri Bhandaru

2. Melanoma—Diagnosis, Subtypes and AJCC Stages
Anand Rotte, Madhuri Bhandaru

3. Etiology
Anand Rotte, Madhuri Bhandaru

4. Melanoma—Treatment
Anand Rotte, Madhuri Bhandaru

Part II. Tumor Immunology

5. Overview of Immune System
Anand Rotte, Madhuri Bhandaru

6. Dendritic Cells
Anand Rotte, Madhuri Bhandaru

7. T-Lymphocytes
Anand Rotte, Madhuri Bhandaru

8. Mechanisms of Immune Evasion by Cancer
Anand Rotte, Madhuri Bhandaru

Part III. Immune Based Drugs Approved for Treatment of Melanoma

9. Interferon-α2b
Anand Rotte, Madhuri Bhandaru

10. Interleukin-2
Anand Rotte, Madhuri Bhandaru

11. Ipilimumab
Anand Rotte, Madhuri Bhandaru

12. Nivolumab
Anand Rotte, Madhuri Bhandaru

13. Pembrolizumab
Anand Rotte, Madhuri Bhandaru

14. Talimogene Laherparepvec
Anand Rotte, Madhuri Bhandaru

Part IV. Ongoing Research

15. Promising Immunotherapeutic Approaches in Clinical Trials
Anand Rotte, Madhuri Bhandaru

Part V. Challenges

16. Challenges of Immunotherapy
Anand Rotte, Madhuri Bhandaru

Nyckelord: Biomedicine, Cancer Research, Oncology