Next-Generation Therapies and Technologies for Immune-Mediated Inflammatory Diseases

Part I. Diagnosis, Patient Stratification and Biomarkers

1. A Tale of Two Worlds
Michael D. Lockshin

2. Biomarkers in Clinical Trials for Rheumatoid Arthritis
Gregory J. Dennis, Gonzalo Fernandez, Heather Iocca, Holly Hilton

3. The Role of Microparticles as Biomarkers in the Development of Therapy for Autoimmune Disease
David S. Pisetsky

Part II. Genomic Medicine

4. The Future for Genomic Medicine in Inflammatory Diseases
Chris Kitson

Part III. Bispecific Antibodies

5. Bispecific Antibodies
Alain C. Tissot, Ulrich Brinkmann

Part IV. Cross-Functional Targets

6. Targeting CD13 with Asn-Gly-Arg (NGR) Peptide-Drug Conjugates
Angelo Corti, Martina Fiocchi, Flavio Curnis

7. Energy Homeostasis of Immune Cells: Translating Cell Bioenergetics into Clinical Application in Rheumatoid Arthritis
Mauricio Rosas-Ballina

8. The Intestinal Microbiome, the Immune System and Spondyloarthropathy
Mary-Ellen Costello, Matthew A. Brown

9. Stem Cell Therapy in the Treatment of Rheumatic Diseases and Application in the Treatment of Systemic Lupus Erythematosus
Patrick S. C. Leung, Zongwen Shuai, Bin Liu, Shang An Shu, Lingyun Sun

Nyckelord: Biomedicine, Immunology, Pharmaceutical Sciences/Technology, Gene Therapy, Pharmacy