Bipolar Depression: Molecular Neurobiology, Clinical Diagnosis, and Pharmacotherapy

Part I. Bipolar Depression: Clinical Phenotype and Course of Illness

1. The History of Bipolar Disorder
Philip B. Mitchell

2. The Clinical Diagnosis of Bipolar Depression
Gordon Parker

3. Course and Outcome of Bipolar Disorder: Focus on Depressive Aspects
Rodrigo Escalona, Mauricio Tohen

4. Suicide and Bipolar Disorder
Zoltán Rihmer, Péter Döme

Part II. Bipolar Depression: Neurobiology

5. The Genetic Basis of Bipolar Disorder
Liping Hou, Francis J. McMahon

6. Understanding the Neurobiology of Bipolar Depression
Araba F. Chintoh, L. Trevor Young

7. Chronotherapeutics in Bipolar and Major Depressive Disorders: Implications for Novel Therapeutics
Wallace C. Duncan

8. Neuroimaging Studies of Bipolar Depression: Therapeutic Implications
Jonathan Savitz, Harvey M. Morris, Wayne C. Drevets

Part III. Acute and Long-term Treatment of Bipolar Depression

9. Pharmacological Treatment of Acute Bipolar Depression
Gary S. Sachs

10. Pharmacological Treatment of the Maintenance Phase of Bipolar Depression: Efficacy and Side Effects
Keming Gao, Renrong Wu, Joseph R. Calabrese

11. Non-pharmacological Somatic Treatments for Bipolar Depression
Harold A. Sackeim

12. Potential Novel Treatments in Bipolar Depression
Rodrigo Machado-Vieira, Ioline D. Henter, Husseini K. Manji, Carlos A. Zarate

Part IV. Treatment of Bipolar Disorder in Special Populations

13. Treatment of Bipolar Disorder in Special Populations
John L. Beyer, K. Ranga R. Krishnan

14. Treatment of Childhood-Onset Bipolar Disorder
Dana Baker Kaplin, Robert L. Findling

15. The Management of Bipolar Disorder During and After Pregnancy
Jennifer L. Payne

Nyckelord: Biomedicine, Pharmacology/Toxicology, Psychopharmacology, Neurosciences