Studies on Alzheimer's Disease

Part I. Hypotheses

1. Oxidative Stress: Impact in Neuroscience Research
Helmut Sies

2. Oxidative Stress and Alzheimer’s Disease
Rudy J. Castellani, Bei-Xu Li, Amna Farshori, Georgy Perry

3. Inflammation and Oxidation: A Link in Alzheimer’s Disease Pathogenesis
Kenneth Hensley

4. GAPDH: β-Amyloid Mediated Iron Accumulation in Alzheimer’s Disease: A New Paradigm for Oxidative Stress Induction in Neurodegenerative Disorders
Michael A. Sirover

5. Aβ in Mitochondria—One Piece in the Alzheimer’s Disease Puzzle
Maria Ankarcrona

6. The Role of the Plasma Membrane Redox System in the Pathogenesis of Alzheimer’s Disease
Sara M. Hancock, David I. Finkelstein, Ashley I. Bush, Paul A. Adlard

Part II. Mechanisms

7. Metal Dysfunction in Alzheimer’s Disease
Rosanna Squitti, Mariacristina Siotto, Carlo Salustri, Renato Polimanti

8. Brain Oxidative Stress in the Pathogenesis and Progression of Alzheimer’s Disease
Rukhsana Sultana, Aaron M. Swomley, D. Allan Butterfield

9. Cholesterol Metabolism and Oxidative Stress in Alzheimer’s Disease
Luigi Iuliano, Valerio Leoni

10. Brain Hypometabolism, Oxidative Stress, Maternal Transmission, and Risk of Late-Onset Alzheimer’s Disease
Lisa Mosconi, John Murray, Pauline McHugh, Mony Leon

11. Stress and HPA Axis Dysfunction in Alzheimer’s Disease
Yash B. Joshi, Domenico Praticò

Part III. Clinics

12. Diabetes Mellitus and Its Impact on Sporadic Alzheimer’s Disease
Weili Xu

13. Peripheral Biomarkers of Oxidative Stress in Alzheimer’s Disease
Fabio Domenico, Marzia Perluigi

14. Nutrition, Lifestyle and Oxidative Stress: Prevention of Alzheimer’s Disease
M. Cristina Polidori, Ludger Pientka

15. Are Antioxidant Food and Nutrients Useful in Preventing Cognitive Decline?
Luc Letenneur, Catherine Feart, Pascale Barberger-Gateau

16. Antioxidant Clinical Trials in Mild Cognitive Impairment and Alzheimer’s Disease
Patrizia Mecocci, M. Cristina Polidori, Domenico Praticó

Nyckelord: Life Sciences, Oxidative Stress, Cell Biology, Geriatrics/Gerontology