Targeted Therapeutics in Melanoma

1. Molecular Targets and Subtypes in Melanoma
Michael A. Davies

2. Melanoma Genomics
Mohammed Kashani-Sabet

3. Predictive Biomarkers as a Guide to Future Therapy Selection in Melanoma
Thomas F. Gajewski

4.
KIT as a Therapeutic Target for Melanoma
Nageatte Ibrahim, F. Stephen Hodi

5. Targeted Inhibition of B-Raf
Paul B. Chapman, Keith Flaherty

6. The Notch and β-Catenin Pathways
John T. Lee, Meenhard Herlyn

7. STAT3 and Src Signaling in Melanoma
Maciej Kujawski, Gregory Cherryholmes, Saul J. Priceman, Hua Yu

8. Targeting the mTOR, PI3K, and AKT Pathways in Melanoma
Kim A. Margolin

9. Targeting Apoptotic Pathways in Melanoma
Peter Hersey, Xu Dong Zhang

10. Anti-Angiogenesis Therapy in Melanoma
Daniel S. Chen

11. Melanoma Antigens Recognized by T Lymphocytes
Nicolas Baren, Jean-François Baurain, Francis Brasseur, Pierre G. Coulie

12. Melanoma Vaccines
Pedro Romero, Daniel E. Speiser

13. Adoptive Cell Therapy for the Treatment of Metastatic Melanoma
Jessica Ann Chacon, Patrick Hwu, Laszlo G. Radvanyi

14. Anti-CTLA-4 Monoclonal Antibodies
Arvin S. Yang, Jedd D. Wolchok

15. Anti-PD-1 and Anti-B7-H1/PD-L1 Monoclonal Antibodies
Evan J. Lipson, Janis M. Taube, Lieping Chen, Suzanne L. Topalian

16. Treatment of Melanoma with Agonist Immune Costimulatory Agents
Andrew Weinberg, Robert H. Vonderheide, Mario Sznol

17. Novel Cytokines for Immunotherapy of Melanoma
Shailender Bhatia, John A. Thompson

18. Modulating the Tumor Microenvironment
Carl E. Ruby, Howard L. Kaufman

Nyckelord: Medicine & Public Health, Oncology, Cancer Research