Chemical Carcinogenesis

1. Historical Overview of Chemical Carcinogenesis
Ronald G. Harvey

2. Multistage Carcinogenesis
Erika L. Abel, John DiGiovanni

3. Tobacco Smoke Carcinogens and Lung Cancer
Stephen S. Hecht

4. Mechanisms of Estrogen Carcinogenesis: Modulation by Botanical Natural Products
Judy L. Bolton

5. Heterocyclic Aromatic Amines: Potential Human Carcinogens
Robert J. Turesky

6. Aflatoxin and Hepatocellular Carcinoma
John D. Groopman, Gerald N. Wogan

7. Metabolic Activation of Chemical Carcinogens
Trevor M. Penning

8. Detoxication of Chemical Carcinogens and Chemoprevention
Melinda S. Yates, Thomas W. Kensler

9. Covalent Polycyclic Aromatic Hydrocarbon–DNA Adducts: Carcinogenicity, Structure, and Function
Suse Broyde, Lihua Wang, Yuqin Cai, Lei Jia, Robert Shapiro, Dinshaw J. Patel, Nicholas E. Geacintov

10. Oxidation and Deamination of DNA by Endogenous Sources
Peter C. Dedon

11. Lipid Peroxide–DNA Adducts
Seon Hwa Lee, Ian A. Blair

12. Chemical Carcinogenesis and Epigenetics
Agus Darwanto, Jonathan D. Ornam, Victoria Valinluck Lao, Lawrence C. Sowers

13. Nucleotide Excision Repair from Bacteria to Humans: Structure–Function Studies
Ye Peng, Hong Wang, Lucas Santana-Santos, Caroline Kisker, Bennett Houten

14. Base-Excision Repair: Role of DNA Polymerase β in Late-Stage Base Excision Repair
Kenjiro Asagoshi, Samuel H. Wilson

15.
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6-Alkylguanine-DNA Alkyltransferase
Anthony E. Pegg, Sreenivas Kanugula, Natalia A. Loktionova

16. Bypass DNA Polymerases
Jeong-Yun Choi, Robert L. Eoff, F. Peter Guengerich

17. Mutagenesis: The Outcome of Faulty Replication of DNA
Ashis K. Basu

18. p53 and Ras Mutations in Cancer and Experimental Carcinogenesis
Zahidur Abedin, Sushmita Sen, Elise Morocco, Jeffrey Field

Nyckelord: Biomedicine, Cancer Research, Pharmacology/Toxicology