Tumor Models in Cancer Research

1. Perspectives on the History and Evolution of Tumor Models
Shannon Decker, Edward Sausville

2. Murine L1210 and P388 Leukemias
William R. Waud

3. Transplantable Syngeneic Rodent Tumors: Solid Tumors in Mice
Lisa Polin, Thomas H. Corbett, Bill J. Roberts, Alfred J. Lawson, Wilbur R. Leopold, Kathryn White, Juiwanna Kushner, Stuart Hazeldine, Richard Moore, James Rake, Jerome P. Horwitz

4. B16 Murine Melanoma: Historical Perspective on the Development of a Solid Tumor Model
Enrique Alvarez

5. Human Tumor Xenograft Efficacy Models
Ming Liu, Daniel Hicklin

6. Imaging the Steps of Metastasis at the Macro and Cellular Level with Fluorescent Proteins in Real Time
Robert M. Hoffman

7. Patient-Derived Tumor Models and Explants
Heinz-Herbert Fiebig, Angelika M. Burger

8. The Pediatric Preclinical Testing Program
Christopher L. Morton, Peter J. Houghton

9. Imaging Efficacy in Tumor Models
Vinod Kaimal, Wilbur R. Leopold, Patrick McConville

10. Mammary Cancer in Rats
Henry J. Thompson

11. Animal Models of Melanoma
Ene T. Fairchild, William E. Carson

12. Experimental Animal Models for Investigating Renal Cell Carcinoma Pathogenesis and Preclinical Therapeutic Approaches
Gilda G. Hillman

13. Animal Models of Mesothelioma
Harvey I. Pass, Joseph B. Pincus, Michele Carbone, Magdalena Plasilova

14. The Use of Mouse Models to Study Leukemia/Lymphoma and Assess Therapeutic Approaches
William Siders

15. Spontaneous Companion Animal (Pet) Cancers
David M. Vail, Douglas H. Thamm

16. Genetically Engineered Mouse Models of Pancreatic Ductal Adenocarcinoma
Aram F. Hezel, Nabeel Bardeesy

17. Transgenic Adenocarcinoma of the Mouse Prostate: A Validated Model for the Identification and Characterization of Molecular Targets and The Evaluation of Therapeutic Agents
Sharon D. Morgenbesser

18. The Utility of Transgenic Mouse Models for Cancer Prevention Research
Stephen D. Hursting, Laura M. Lashinger, Powel H. Brown, Susan N. Perkins

19. Models for Evaluation of Targeted Therapies of Invasive and Metastatic Disease
Suzanne A. Eccles

20. Animal Models of Toxicities Caused by Anti-Neoplastic Therapy
Stephen T. Sonis, Gregory Lyng, Kimberly Pouliot

21. Bone Marrow as a Critical Normal Tissue that Limits Drug Dose/Exposure in Preclinical Models and the Clinic
Ralph E. Parchment

22. Anesthetic Considerations for the Study of Murine Tumor Models
Thies Schroeder, Siqing Shan, Mark W. Dewhirst

23. Preclinical Tumor Response End Points
Beverly A. Teicher

24. Tumor Cell Survival
Sara Rockwell

25. Apoptosis In Vivo
L. C. Stephens, L. Milas, K. K. Ang, K. A. Mason, R. E. Meyn

26. Transparent Window Models and Intravital Microscopy: Imaging Gene Expression, Physiological Function and Therapeutic Effects in Tumors
Rakesh K. Jain, Lance L. Munn, Dai Fukumura

Nyckelord: Biomedicine, Cancer Research, Pharmacology/Toxicology