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Yuan, Jason X. -J.

Membrane Receptors, Channels and Transporters in Pulmonary Circulation

Yuan, Jason X. -J. - Membrane Receptors, Channels and Transporters in Pulmonary Circulation, e-bok


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ISBN: 9781607615002

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Table of contents

1. The Role of Ion Channels in Hypoxic Pulmonary Vasoconstriction
E. Kenneth Weir, Jésus A. Cabrera, Saswati Mahapatra, Douglas A. Peterson, Zhigang Hong

2. Two-Pore Domain K+ Channels and Their Role in Chemoreception
Keith J. Buckler

3. Intricate Interaction Between Store-Operated Calcium Entry and Calcium-Activated Chloride Channels in Pulmonary Artery Smooth Muscle Cells
Abigail S. Forrest, Jeff E. Angermann, Rajesh Raghunathan, Catherine Lachendro, Iain A. Greenwood, Normand Leblanc

4. The Role of Intracellular Ion Channels in Regulating Cytoplasmic Calciumin Pulmonary Arterial Mmooth Muscle: Which Store and Where?
A. Mark Evans

5. Ca2+ Oscillations Regulate Contraction Of Intrapulmonary Smooth Muscle Cells
Michael J. Sanderson, Yan Bai, Jose Perez-Zoghbi

6. Introduction to TRP Channels: Structure, Function, and Regulation
Michael Y. Song, Jason X.-J. Yuan

7. Physiological Functions of Transient Receptor Potential Channels in Pulmonary Arterial Smooth Muscle Cells
Xiao-Ru Yang, Mo-Jun Lin, James S. K. Sham

8. The Contribution of TRPC1 and STIM1 to Capacitative Ca2+ Entry in Pulmonary Artery
Lih Chyuan Ng, Judith A. Airey, Joseph R. Hume

9. Store-Operated Calcium Entry Channels in Pulmonary Endothelium: The Emerging Story of TRPCS and Orai1
Donna L. Cioffi, Christina Barry, Troy Stevens

10. TRPM2 Channel Regulates Endothelial Barrier Function
Claudie M. Hecquet, Gias U. Ahmmed, Asrar B. Malik

11. A Proposed Mitochondrial–Metabolic Mechanism for Initiation and Maintenance of Pulmonary Arterial Hypertension in Fawn-Hooded Rats: The Warburg Model of Pulmonary Arterial Hypertension
Jalees Rehman, Stephen L. Archer

12. The Role of Classical Transient Receptor Potential Channels in the Regulation of Hypoxic Pulmonary Vasoconstriction
B. Fuchs, A. Dietrich, T. Gudermann, H. Kalwa, F. Grimminger, N. Weissmann

13. Developmental Regulation of Oxygen Sensing and Ion Channels in the Pulmonary Vasculature
David N. Cornfield

14. Hypoxic Regulation of Ion Channels and Transporters in Pulmonary Vascular Smooth Muscle
Larissa A. Shimoda

15. CLC-3 Chloride Channels in the Pulmonary Vasculature
Joseph R. Hume, Ge-Xin Wang, Jun Yamazaki, Lih Chyuan Ng, Dayue Duan

16. Role of Bone Morphogenetic Protein Receptors in the Development of Pulmonary Arterial Hypertension
Nicholas W. Morrell

17. Cross Talk Between Smad, MAPK, and Actin in the Etiology of Pulmonary Arterial Hypertension
James West

18. Notch Signaling in Pulmonary Hypertension
Patricia A. Thistlethwaite, Xiaodong Li, Xiaoxue Zhang

19. Rho Kinase-Mediated Vasoconstriction in Pulmonary Hypertension
Ivan F. McMurtry, Kohtaro Abe, Hiroki Ota, Karen A. Fagan, Masahiko Oka

20. The Serotonin Hypothesis of Pulmonary Hypertension Revisited
Margaret R. MacLean, Yvonne Dempsie

21. Impaired Vascular Endothelial Growth Factor Signaling in the Pathogenesis of Neonatal Pulmonary Vascular Disease
Steven H. Abman

22. Mitochondrial Regulation of Oxygen Sensing
Navdeep S. Chandel

23. Reactive Oxygen Species and RhoA Signaling in Vascular Smooth Muscle: Role in Chronic Hypoxia-Induced Pulmonary Hypertension
Thomas C. Resta, Brad R. S. Broughton, Nikki L. Jernigan

24. Polyamine Regulatory Pathways as Pharmacologic Targets in Pulmonary Arterial Hypertension
Mark N. Gillespie, Jack W. Olson

25. 5-HT Receptors and KV Channel Internalization
Angel Cogolludo, Francisco Perez-Vizcaino

26. KCNQ Potassium Channels: New Targets for Pulmonary Vasodilator Drugs?
Alison M. Gurney, Shreena Joshi, Boris Manoury

27. Receptor Tyrosine Kinase Inhibitors in Rodent Pulmonary Hypertension
Liliana Moreno-Vinasco, Joe G. N. Garcia

28. PDGF Receptor and its Antagonists: Role in Treatment of PAH
Friedrich Grimminger, Ralph Theo Schermuly

29. PPARγ and the Pathobiology of Pulmonary Arterial Hypertension
Marlene Rabinovitch

30. Targeting TASK-1 Channels as a Therapeutic Approach
Andrea Olschewski

31. Pharmacological Targets for Pulmonary Vascular Disease: Vasodilation versus Anti-Remodelling
Matthew Thomas

Nyckelord: Medicine & Public Health, Vascular Surgery, Cell Biology, Medical Biochemistry

Advances in Experimental Medicine and Biology
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