Principles of Molecular Oncology

1. Selecting the Right Targets for Cancer Therapy
Miguel H. Bronchud

2. Clinical Importance of Prognostic Factors
N. Lynn Henry, Daniel F. Hayes

3. Genetic Markers in Sporadic Tumors
Elena Tamborini, Federica Perrone, Milo Frattini, Tiziana Negri, Antonella Aiello, Annunziata Gloghini, Antonino Carbone, Silvana Pilotti, Marco A. Pierotti

4. Genetic Markers in Breast Tumors with Hereditary Predisposition
Tatyana A. Grushko, Olufunmilayo I. Olopade

5. Circulating Tumor Markers
Alan Horwich, Gill Ross

6. Antibody-Based Proteomics Analysis of Tumor Cell Signaling Pathways
Steven Pelech, Hong Zhang

7. Gene Expression Arrays for Pathway Analysis in Cancer Research
Xiang Sean Yu, Raymond K. Blanchard, Yexun Wang, Min You

8. Signaling Pathways in Cancer
Daniel Kalderon

9. Estrogen Receptor Pathways and Breast Cancer
Jing Peng, V. Craig Jordan

10. Cyclin-Dependent Kinases and Their Regulators as Potential Targets for Anticancer Therapeutics
Marcos Malumbres

11. Angiogenesis Switch Pathways
Jaume Piulats, Francesc Mitjans

12. Apoptosis Pathways and New Anticancer Agents
Frank A.E. Kruyt, Jose A. Rodriguez, Giuseppe Giaccone

13. Genomic Instability, DNA Repair Pathways and Cancer
Gabriel Capellá, Josep Balart, Miguel Angel Peinado

14. Epigenomics and Cancer
Isabel López Silanes, Manel Esteller

15. Harnessing the Power of Immunity to Battle Cancer: Much Ado about Nothing or All's Well That Ends Well?
Angelo A. Cardoso

16. Aurora Kinases: A New Target for Anticancer Drug Development
Teresa Macarulla, Francisco Javier Ramos, Josep Tabernero

17. Emerging Molecular Therapies: Drugs Interfering With Signal Transduction Pathways
Alison H.M. Reid, Richard Baird, Paul Workman

18. Suicide Gene Therapy
Silke Schepelmann, Ion Niculescu-Duvaz, Caroline J. Springer

19. Genotypes That Predict Toxicity and Genotypes That Predict Efficacy of Anticancer Drugs
Rosario García-Campelo, Miquel Tarón, Itziar De Aguirre, Pedro Méndez, Rafael Rosell

20. A Personal Account of the Chemoprevention of Breast Cancer: Possible or Not Possible?
V. Craig Jordan

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Nyckelord: MEDICAL / Public Health MED078000