Retinal Degenerations

I.Living with Retinal Degeneration

1. Coping With Retinal Degeneration
Gordon Cousins, James Cape

II.Degenerative Diseases of the Retina

2. Epidemiology of Age-Related Macular Degeneration Early in the 21st Century
Jie Jin Wang, Paul Mitchell, Ronald Klein

3. Leber Congenital Amaurosis
Robert K. Koenekoop

4. Macular Degeneration
Peter E. Liggett, Alejandro J. Lavaque

5. Stargardt Disease
Rando Allikmets

6. X-Linked Juvenile Retinoschisis
Bernhard H. F. Weber, Ulrich Kellner

7. Retinal Degeneration in Usher Syndrome
David S. Williams

8. Mouse Models of RP
Bo Chang, Norman L. Hawes, Muriel T. Davisson, J. R. Heckenlively

III.Mechanisms Underlying Retinal Degenerations

9. The Impact of Diabetes on Neuronal, Glial, and Vascular Cells of the Retina
Sylvia B. Smith

10. Statins and Age-Related Maculopathy
Gerald McGwin, Cynthia Owsley

11. The Role of Drusen in Macular Degeneration and New Methods of Quantification
R. Theodore Smith, Umer F. Ahmad

12. RPE Lipofuscin
Janet R. Sparrow

13. Genetic Modifiers That Affect Phenotypic Expression of Retinal Diseases
Malia M. Edwards, Dennis M. Maddox, Jungyeon Won, Jürgen K. Naggert, Patsy M. Nishina

14. X-Linked Retinal Dystrophies and Microtubular Functions Within the Retina
Alan F. Wright, Xinhua Shu

15. Synaptic Remodeling in Retinal Degeneration
You-Wei Peng, Fulton Wong

IV.Developing Therapeutic Strategies for Retinal Degenerative Diseases

16. On The Suppression of Photoreceptor Cell Death in Retinitis Pigmentosa
Fiona Kernan, Alex G. McKee, G. Jane Farrar, Peter Humphries

17. Cell-Based Therapies to Restrict the Progress of Photoreceptor Degeneration
Raymond D. Lund, Shaomei Wang

18. Current Status of IPE Transplantation and Its Potential as a Cell-Based Therapy for Age-Related Macular Degeneration and Retinal Dystrophies
Makoto Tamai

19. Recent Results in Retinal Transplantation Give Hope for Restoring Vision
Robert B. Aramant, Norman D. Radtke, Magdalene J. Seiler

20. Stem Cells and Retinal Transplantation
Joanne Yau, Henry Klassen, Tasneem Zahir, Michael Young

21. Application of Encapsulated Cell Technology for Retinal Degenerative Diseases
Weng Tao, Rong Wen

22. Effective Treatment for the Canine RPE65 Null Mutation, a Hereditary Retinal Dystrophy Comparable to Human Leber’s Congenital Amaurosis
Kristina Narfström, Gregory E. Tullis, Mathias Seeliger

23. Neuroprotective Factors and Retinal Degenerations
Joyce Tombran-Tink, Colin J. Barnstable

24. Carbonic Anhydrase Inhibitors as a Possible Therapy for RP17, an Autosomal Dominant Retinitis Pigmentosa Associated With the R14W Mutation, Apoptosis, and the Unfolded Protein Response
George Rebello, Jacquie Greenberg, Raj Ramesar

25. Macular Degeneration—An Addendum
Colin J. Barnstable, Joyce Tombran-Tink

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Nyckelord: MEDICAL / Public Health MED078000