Discoidin Domain Receptors in Health and Disease

Part I. Discoidin Domain Receptor Biology and Roles in Physiology

1. DDRs: Binding Properties, Cell Adhesion and Modulation of Integrin Function
Birgit Leitinger

2. DDRs and Collagen Fibrillogenesis
Gunjan Agarwal

3. DDR Structural Biology
Noritaka Nishida, Ichio Shimada

4. DDR Mouse Models
Kiyoshi Kano, Ken Takeshi Kusakabe, Yasuo Kiso

5. Discoidin Domain Receptors in Invertebrates
Thomas Unsoeld, Jesse Taylor, Harald Hutter

Part II. Discoidin Domain Receptors in Cancer

6. Discoidin Domain Receptors and Disease
Gregory D. Longmore, Whitney R. Grither

7. Discoidin Domain Receptors in Normal Mammary Development and Breast Cancer Progression
Sandamali A. Ekanayaka, Celina G. Kleer, Aliccia Bollig-Fischer, Rodrigo Fernandez-Valdivia, Rafael Fridman

8. Discoidin Domain Receptors in Lung Cancer
Yingtao Zhang, Agnes Malysa, Gerold Bepler

9. DDRs in Healthy and Cancerous Reproductive Systems
Marta Marco, Paul R. Gill

10. Small Molecule Inhibitors of Discoidin Domain Receptors (DDRs)
Xiaoyun Lu, Ke Ding

11. Discoidin Domain Receptor Signalling Networks
Leo K. Iwai, Leo S. Payne, Dina Allam, Paul H. Huang

12. Discoidin Domain Receptor Signaling and Pharmacological Inhibitors
Pedro A. Ruiz-Castro, Duncan Shaw, Gabor Jarai

13. Functions of DDR1 in Epithelial Cell Differentiation
Yi-Chun Yeh, Ming-Jer Tang

Part III. Discoidin Domain Receptors in Other Pathologies

14. Discoidin Domain Receptor 2 in Development of Osteoarthritis
Lin Xu, Peter L. Lee, Yefu Li

15. DDR1 in Renal Function and Disease
Christos Chatziantoniou, Aude Dorison, Jean-Claude Dussaule

16. Discoidin Domain Receptors in Liver Fibrosis
Elvira Olaso, Joana Marquez, Aitor Benedicto, Iker Badiola, Beatriz Arteta

17. The Role of DDRs in Atherosclerosis
Michelle P. Bendeck

18. Discoidin Domain Receptors in Cardiac Development
David E. Justus, Adam Hoffman, Ekaterina Mironova, Alexander Hartman, Jack G. Goldsmith, Jay D. Potts, Edie C. Goldsmith

Nyckelord: Biomedicine, Cancer Research, Medical Microbiology, Medical Biochemistry, Cell Biology