Protein Tyrosine Phosphatases in Cancer

1. Time to Shine the Spotlight on the Protein Tyrosine Phosphatase Family of Signal Transducing Enzymes
Nicholas K. Tonks

2. RPTPs and Cancer
Andrew W. Stoker

3. Non-transmembrane PTPs in Cancer
Wiljan J. A. J. Hendriks, Frank-D Böhmer

4. Role of PTPN11 (SHP2) in Cancer
Gordon Chan, Benjamin G. Neel

5. The Role of TCPTP in Cancer
Tony Tiganis

6. PTP1B: From Metabolism to Cancer
David P. Labbé, Michel L. Tremblay

7. Dual-Specificity Map Kinase (MAPK) Phosphatases (MKPs) and Their Involvement in Cancer
Andrew M. Kidger, Stephen M. Keyse

8. PTEN
Dawid G. Nowak, Lloyd C. Trotman

9. Phosphatase-Independent Functions of the Tumor Suppressor PTEN
Antonella Papa, Pier Paolo Pandolfi

10. The PRL PTPs: Regulating Gene Expression to Reprogram the Cancer Cell
Cameron A. Rogers, Catherine J. Pallen

11. Cdc25 Family Phosphatases in Cancer
Brian Gabrielli, Andrew Burgess

12. Protein-Tyrosine Phosphatases: Linking Metabolism and Cancer
Kendra K. Bence

13. Current Status of PTP-Based Therapeutics
Rongjun He, Zhong-Yin Zhang

Nyckelord: Biomedicine, Cancer Research, Cell Biology, Posttranslational Modification