Studies on Periodontal Disease

Part I. Oxidative Stress in Periodontal Diseases (Basic Science)

1. Reactive Oxygen Species and Antioxidant Systems in Periodontal Disease
Masaichi-Chang-il Lee

2. The Role of Protein Oxidative Modification in Periodontal Diseases
Ryutaro Isoda, Kenji Matsushita

3. Association Between Oxidative Stress and Periodontal Diseases in Animal Model Studies
Manabu Morita, Daisuke Ekuni, Takaaki Tomofuji

4. Expression of Reactive Oxygen Species in Junctional and Pocket Epithelium
Daisuke Ekuni, James D. Firth, Edward E. Putnins

5. DNA Damage Caused by Oral Malodorous Compounds in Periodontal Cells In Vitro: Novel Carcinogenic Pathway
Bogdan Calenic, Ken Yaegaki

6. Apoptotic Pathways Triggered by Oral Malodorous Compounds in Periodontal Cells:Novel Periodontal Pathologic Cause
Bogdan Calenic, Ken Yaegaki

7. The Role of p53 in Carcinogenesis and Apoptosis in Oral Tissues
Ken Yaegaki

8. Physiological Roles of a Periodontopathic Bacterial Membrane-Bound Quinol Peroxidase
Kiyoshi Konishi

Part II. Oxidative Stress in Periodontal Diseases (Clinical Studies)

9. Periodontitis and Oxidative Stress: Human Studies
Luigi Nibali, Brian Henderson, Giovanni Li Volti, Nikos Donos

10. Effects of Periodontal Therapy on Circulating Oxidative Stress
Takaaki Tomofuji, Daisuke Ekuni, Manabu Morita

11. Role of HMGB1 in Periodontal Disease
Noriko Ebe, Miki Hara-Yokoyama, Yuichi Izumi

Part III. Periodontal Diseases and Systemic Diseases (Possible Link to Other Organs)

12. The Inflammation as the Connecting Link Between Systemic Diseases and Periodontal Diseases
Juan Manuel Morillo-Velázquez

13. Periodontitis and Atherosclerosis
Daisuke Ekuni, Takaaki Tomofuji, Manabu Morita

14. Periodontitis and Liver Diseases
Koichiro Irie, Daisuke Ekuni, Takaaki Tomofuji, Manabu Morita

15. Oxidative Stress and Periodontal Disease in Down Syndrome
Tomoko Komatsu, Masaichi-Chang-Il Lee

Part IV. Future Strategies (Control of ROS, Roles of Nutrition/Antioxidants and Application to Dentistry)

16. New Theories and Their Clinical Relevance to the Onset and Development of Periodontal Diseases
Pedro Bullon

17. The Role of Nutrition in Periodontal Diseases
José L. Quiles, Alfonso Varela-López

18. Effects of Antioxidants on Periodontal Disease
Takaaki Tomofuji, Daisuke Ekuni, Shinsuke Mizutani, Manabu Morita

19. Role of Vitamin C and Vitamin E in Periodontal Disease
Hideki Nagata

20. Salivary Biomarkers of Oxidative Stress Associated with Periodontal Diseases
Maria Greabu, Bogdan Calenic

Nyckelord: Life Sciences, Oxidative Stress, Cell Biology, Dentistry, Apoptosis