Immunological Mechanisms and Therapies in Brain Injuries and Stroke

1. Old Dogmas, Surprising Complexities, and Novel Therapeutic Targets
Ulrich Dirnagl

2. The Critical Roles of Immune Cells in Acute Brain Injuries
Peiying Li, Yu Gan, Leilei Mao, Rehana Leak, Jun Chen, Xiaoming Hu

3. Vascular Inflammation in Ischemic Stroke: Adhesion Receptors Controlling Leukocyte–Endothelial Interactions
Stephen F. Rodrigues, D. Neil Granger

4. Immune Cell-Derived Free Radicals in Acute Brain Injury
Purnima Narasimhan, Hiroyuki Sakata, Joo Eun Jung, Tatsuro Nishi, Takuma Wakai, Carolina M. Maier, Pak H. Chan

5. The Complement Cascade in Acute Brain Injury
Michael McDowell, Nicholas Shea, Gaurav Gupta, E. Sander Connolly

6. Matrix Metalloproteinases as an Inflammatory Mediator in the Neurovascular Unit
Changhong Xing, Takakuni Maki, Ji Hae Seo, Ken Arai, Eng H. Lo

7. Toll-Like Receptors in Ischemic Stroke and Other Acute Brain Injuries
Frances Rena Bahjat, Raffaella Gesuete, Mary P. Stenzel-Poore

8. Ion Transporters in Microglial Function: New Therapeutic Targets for Neuroinflammation in Ischemic Stroke?
Hui Yuan, Yejie Shi, Dandan Sun

9. Inflammation After Acute Brain Injuries Affects the Developing Brain Differently than the Adult Brain
David Fernández-López, Zinaida S. Vexler

10. Systemic Immune Responses after Experimental Stroke
Halina Offner, Patricia D. Hurn

11. Infectious Burden and Risk of Stroke
Jorge M. Luna, Mitchell S. V. Elkind

12. Inflammatory Biomarkers in Patients with Acute Brain Injuries
Glen C. Jickling

13. In Vivo Imaging of Neuroinflammation in Acute Brain Injury
Alexander Thiel

14. Inflammation as a Therapeutic Target after Subarachnoid Hemorrhage: Advances and Challenges
Mutsumi Fujii, Sheng Chen, Damon Klebe, Yoshiteru Soejima, Alexander Vakhmyanin, John H. Zhang

15. Minocycline, A Tetracycline Derivative, as a Potential Protective Agent for Acute Stroke
Jari Koistinaho, Milla Koistinaho

16. Tolerization to Brain and Vascular Antigens: Targeting Autoimmunity After Acute Brain Injuries and Preventing Stroke
Kyra J. Becker, John Hallenbeck

17. The Role of PPARγ in Stroke
Xiurong Zhao, Jaroslaw Aronowski

18. CD36: An Inflammatory Mediator in Acute Brain Injury
Sunghee Cho, Maria Febbraio

19. Cool Down the Inflammation: Hypothermia as a Therapeutic Strategy for Acute Brain Injuries
Yama Akbari, Maximilian Mulder, Ali Razmara, Romergryko Geocadin

Nyckelord: Biomedicine, Neurosciences, Neurology, Neurobiology