Molecular Diagnostics

Part I. Oncology

1. Clinical FISH Testing for the Diagnosis of Solid Tumors
Benjamin R. Kipp, Kevin C. Halling

2. Epidermal Growth Factor Receptor Testing in Lung Adenocarcinoma
Neal I. Lindeman

3. The Human Epidermal Growth Factor Receptor 2 (HER2)
Laura J. Tafe, Gregory J. Tsongalis

4. Tamoxifen and Irinotecan Pharmacogenomics
John Logan Black

Part II. Infectious Disease

5. Hepatitis C Virus Testing
Hassan M. E. Azzazy, Karim M. Abdel-Hady

6. Laboratory Testing for HIV Infection: Advances After 28 Years
Joseph Ntumbong Nkeze, Niel T. Constantine, Richard Y. Zhao

7. Detection of Herpes Simplex Virus in Cerebrospinal Fluid Using Real-Time PCR
Thomas F. Smith, Mark J. Espy, Matthew J. Binnicker

8. Toward a Safer Blood Supply: The Impact of Molecular Testing
Niel T. Constantine, Patricia A. Wright, Ahmed Saleh, Anna DeMarinis

Part III. Genetics

9. Chromosome Microarrays
Umut Aypar, Swaroop Aradhya, Hutton Kearney, Christa Martin, Sarah South, Eric C. Thorland

10.
BRCA1 and BRCA2 Testing in Inherited Breast Cancer
Karla R. Bowles, Eric Rosenthal

11. Cystic Fibrosis: Carrier Testing, Newborn Screening, and Diagnostic Testing
W. Edward Highsmith

12. Newborn Screening by Tandem Mass Spectrometry and Molecular Confirmation
Sean Hofherr, Devin Oglesbee

Part IV. Future Directions: The Test That Will Change Everything—Again

13. Next Generation Clinical Diagnostics: The Sequence of Events
Nicole Hoppman, David I. Smith, Eric W. Klee, Matthew J. Ferber

Nyckelord: Medicine & Public Health, Pathology, Oncology, Infectious Diseases