Resistance to Immunotherapeutic Antibodies in Cancer

1. Resistance to Anticancer Antibodies: From Mechanisms to Solutions
Lina Reslan, Charles Dumontet

2. Tumor Antigen-Specific Monoclonal Antibody-Based Immunotherapy, Cancer Initiating Cells and Disease Recurrence
Yangyang Wang, Francesco Sabbatino, Ling Yu, Elvira Favoino, Xinhui Wang, Matteo Ligorio, Soldano Ferrone, Joseph H. Schwab, Cristina R. Ferrone

3. Overcoming Resistance to Therapeutic Antibodies by Targeting Fc Receptors
Emily L. Williams, Sean H. Lim, Stephen A. Beers, Peter W. Johnson, Jonathan C. Strefford, Martin J. Glennie, Mark S. Cragg

4. Understanding the Mechanisms of Resistance to Rituximab: Paving the Road for the Development of Therapeutic Strategies to Overcome Rituximab-Resistance
Francisco J. Hernandez-Ilizaliturri, Myron S. Czuczman

5. Tumor Resistance to Antibody-Mediated Immunotherapy and Reversal of Resistance: Rituximab as Prototype
Benjamin Bonavida

6. Resistance to the Anti-EGFR Therapy, Beyond KRAS, in Patients with Metastatic Colorectal Cancer
Zacharenia Saridaki, John Souglakos

7. Overcoming Resistance of Melanoma to Immunotherapy with Monoclonal Antibodies Against Checkpoints Inhibitors
Peter Hersey, Stuart Gallagher, Branka Mijatov

8. Strategies to Overcome TRAIL Resistance in Cancer
Simone Fulda

9. Unnatural Amino Acid Antibody Conjugates as Next Generation Biologics
Vaughn Smider

10. Antibody-Drug Conjugates: Can Coupling Cytotoxicity and Specificity Overcome Therapeutic Resistance?
Penelope M. Drake, David Rabuka

Nyckelord: Biomedicine, Cancer Research, Molecular Medicine, Immunology, Antibodies