Advances in DNA Repair in Cancer Therapy

1. Repair of DNA Interstrand Cross-links Produced by Cancer Chemotherapeutic Drugs
Anderson T. Wang, Peter J. McHugh, John A. Hartley

2. DNA-PK, a Pharmacological Target in Cancer Chemotherapy and Radiotherapy?
Bernard Salles, Patrick Calsou, Gladys Mirey

3. Growth Factor Receptor Signaling, DNA Damage Response, and Cancer Cell Susceptibility to Chemotherapy and Relapses
Moulay Alaoui-Jamali, Amine Saad, Gerald Batist

4. The Relationship Between DNA-Repair Genes, Cellular Radiosensitivity, and the Response of Tumors and Normal Tissues to Radiotherapy
David Murray, Matthew Parliament

5. Important Roles of ERCC1 in DNA Repair and Targeted Therapy
Jennifer J. Hu, Joseph Garza, Sathish K. Srinivasan, Ann Alyssa Kurian, Feng Gong

6. The Role of BRCA1 and BRCA2 in Anticancer Drug Therapy
Andrew Y. Shuen, Jorge S. Reis-Filho, William D. Foulkes

7. DNA-PK in CLL Chemotherapy
L. Amrein, D. Davidson, R. Aloyz, L. Panasci

8. Poly(ADP) Ribose Polymerase at the Interface of DNA Damage Signaling and DNA Repair
Jana Krietsch, Michèle Rouleau, Michel Lebel, Guy Poirier, Jean-Yves Masson

9. Cellular Protection Against the Antitumor Drug Bleomycin
Dindial Ramotar, Mustapha Aouida

10. ATR as a Therapeutic Target
Fiona K. Middleton, Nicola J. Curtin

11. Telomeres, Telomerase, and DNA Damage Response in Cancer Therapy
Raina A. Tamakawa, Helen B. Fleisig, Judy M. Y. Wong

12. RAD51 Is a Key Protein of DNA Repair and Homologous Recombination in Humans
Alexander V. Mazin, Olga M. Mazina

Nyckelord: Biomedicine, Cancer Research, Molecular Medicine