Renal Cell Carcinoma

1. The Genetic Basis of Kidney Cancer and Implications for Targeted Therapies
Laura S. Schmidt, Ramaprasad Srinivasan, W. Marston Linehan

2. Molecular Biology of Clear Cell Renal Carcinoma
William G. Kaelin

3. HIF Biology in RCC: Implications for Signaling, Disease Progression, and Treatment
W. Kimryn Rathmell

4. Tissue Biomarkers in Renal Cell Carcinoma: Intermediate Endpoints in the Selection of Targeted Agents for RCC
Brittany Bahamon, Sabina Signoretti

5. Molecular Characterization of Renal Cell Carcinoma
Bin Tean Teh, Leslie J. Farber, Kyle Furge

6. Targeting the VEGF Pathway in Renal Cell Carcinoma
Cristina Suarez, Brian I. Rini

7. Angiopoietins and Other Non-VEGF Antiangiogenic Targets in Advanced Renal Cell Carcinoma
C. Lance Cowey, Thomas E. Hutson

8. Research Translation and Personalized Medicine
James Brugarolas

9. Epigenetic Targeting and Histone Deacetylase Inhibition in RCC
Swathi Ramakrishnan, Roberto Pili

10. C-MET as a Novel Target for the Treatment of Renal Cell Carcinoma
Hema Vankayala, Patricia LoRusso, Ulka Vaishampayan

11. Characterizing and Modulating the Tumor Microenvironment in Renal Cell Carcinoma: Potential Therapeutic Strategies
Sumanta Kumar Pal, Karen Reckamp, Hua Yu, Robert A. Figlin, Robert A. Figlin, Robert A. Figlin

12. Carbonic Anhydrase IX: Its Role as a Biomarker, Diagnostic, and Therapeutic Target in Renal Cell Carcinoma
E. Oosterwijk, A. B. Stillebroer, P. F. A. Mulders

13. Presurgical Therapy for Renal Cell Carcinoma and Implications for Window-of-Opportunity Trials
Hyung L. Kim, Edwin M. Posadas, Robert A. Figlin, Robert A. Figlin, Robert A. Figlin

14. Mechanisms of Resistance to VEGF-Directed Therapy and Implications for Future Trial Design
James W. Mier

15. Vaccine-Based Immunotherapy and Targeting the Tumor Microenvironment in Renal Cell Carcinoma
Johannes Vieweg

Nyckelord: Biomedicine, Cancer Research, Pharmacology/Toxicology