Engineering in Translational Medicine

1. Engineering in Translational Medicine: An Introduction
Weibo Cai

Part I. Cell and Tissue Engineering

2. Stem Cells: The Holy Grail of Regenerative Medicine
Ram K. Singh, Snehal M. Gaikwad, Subhoshree Chatterjee, Pritha Ray

3. Engineering T Cells to Target Tumor Cells
Hiroki Torikai, Judy S. Moyes, Laurence J. N. Cooper

4. Engineering Biomaterials for Anchorage-Dependent and Non-anchorage-Dependent Therapeutic Cell Delivery in Translational Medicine
Wenyan Leong, Dong-An Wang

5. Tissue Engineering Applications for Peripheral Nerve Repair
Hakan Orbay, Weibo Cai

6. Structure, Function, and Development of Blood Vessels: Lessons for Tissue Engineering
Hamisha Ardalani, Amir H. Assadi, William L. Murphy

7. Engineering Gene-Activated Matrices for the Repair of Articular Cartilage Defect
Junfeng Zhang, Zhen Huang

Part II. Genetic and Protein Engineering

8. Engineering Luciferases for Assays and Imaging
Andreas M. Loening, Zachary F. Walls

9. Engineered Split Reporter Systems for Molecular Imaging of Protein–Protein Interactions in Living Subjects
Tarik F. Massoud, Ramasamy Paulmurugan

10. Engineering Aspects of Bioluminescence Resonance Energy Transfer Systems
Abhijit De, Rohit Arora, Akshi Jasani

11. Antibody Engineering in Translational Medicine
Eliane Fischer

12. Engineered Affibodies in Translational Medicine
Xiang Hu, Hongguang Liu, Zhen Cheng

13. Alternative Protein Scaffolds for Molecular Imaging and Therapy
Benjamin J. Hackel

14. Engineering Multivalent and Multispecific Protein Therapeutics
Cassie J. Liu, Jennifer R. Cochran

15. Engineering Aptamers for Biomedical Applications: Part I
Ya Cao, Genxi Li

16. Engineering Aptamers for Biomedical Applications: Part II
Laura Cerchia, Luciano Cellai, Vittorio Franciscis

17. Engineering DNA Vaccines for Cancer Therapy
Brian M. Olson, Douglas G. McNeel

Part III. Nanoengineering

18. Multifunctional Nanoscale Delivery Systems for Nucleic Acids
Richard Conroy, Belinda Seto

19. Engineering Nanomaterials for Biosensors and Therapeutics
Tse-Ying Liu, Chun-Liang Lo, Chih-Chia Huang, Syue-Liang Lin, C. Allen Chang

20. Engineering Fluorescent Nanoparticles for Biomedical Applications
Oscar F. Silvestre, Xiaoyuan Chen

21. Magnetic Nanoparticles for Biomedical Applications: From Diagnosis to Treatment to Regeneration
Yu Gao, Yi Liu, Chenjie Xu

22. Engineering Upconversion Nanoparticles for Biomedical Imaging and Therapy
Feng Chen, Wenbo Bu, Weibo Cai, Jianlin Shi

23. Engineering of Mesoporous Silica Nanoparticles for In Vivo Cancer Imaging and Therapy
Feng Chen, Weibo Cai, Hao Hong

24. Engineering Carbon Nanomaterials for Stem Cell-Based Tissue Engineering
Tapas R. Nayak, Weibo Cai

25. Engineering Peptide-based Carriers for Drug and Gene Delivery
Jo-Ann Chuah, David L. Kaplan, Keiji Numata

26. Activation Approaches on Delivery of Imaging and Therapeutic Agents
Mitulkumar A. Patel, Benedict Law

27. Opportunities for New Photodynamic Molecular Beacon Designs
Kun Lou, Jonathan F. Lovell

Part IV. Biomedical Instrumentation

28. Engineering the Next-Generation PET Detectors
Arne Vandenbroucke, Craig S. Levin

29. Photoacoustic Imaging: Development of Imaging Systems and Molecular Agents
Adam de la Zerda

30. Engineering Miniature Imaging Instruments
Zhen Qiu, Thomas D. Wang

31. Engineering Small Animal Conformal Radiotherapy Systems
Magdalena Bazalova, Edward E. Graves

Part V. Theranostics and Other Novel Approaches

32. Plasmonic Nanobubbles for Cancer Theranostics
Ekaterina Y. Lukianova-Hleb, Dmitri O. Lapotko

33. Cell-based Microfluidic Assays in Translational Medicine
Eric K. Sackmann, Benjamin P. Casavant, S. Farshid Moussavi-Harami, David J. Beebe, Joshua M. Lang

34. Engineering of Photomanipulatable Hydrogels for Translational Medicine
Mingtao He, Yan Zhang

35. Engineering AApeptides for Translational Medicine
Haifan Wu, Jianfeng Cai

Nyckelord: Engineering, Biomedical Engineering, Imaging / Radiology, Biomaterials, Biophysics and Biological Physics, Medical and Radiation Physics