Insulin Resistance and Cancer

1. Insulin and the Physiology of Carbohydrate Metabolism
Sandra Pereira, Adria Giacca

2. Insulin/IGF-1 Signaling Nodes and their Role in Carcinogenesis
Cullen M. Taniguchi, C. Ronald Kahn

3. The Mechanisms and Impact of Obesity and Insulin Resistance on Breast Cancer Incidence
Deborah J. Clegg

4. Obesity and Cancer: Epidemiology
Melinda L. Irwin

5. Insulin, Insulin Resistance, and Cancer Associations
Lorraine Lipscombe

6. Animal Models of Hyperinsulinemia, Insulin Resistance, and Cancer
Ruslan Novosyadlyy, Archana Vijayakumar, Yvonne Fierz, Derek LeRoith

7. Potential Mechanisms Linking Insulin to Cancer
Yael Babichev, Sarah Khalid, I. George Fantus

8. Actions of Insulin As a Survival and Growth Factor: Akt, mTOR, and Regulation of Translation
Luc Furic, Mark Livingstone, Ivan Topisirovic, Nahum Sonenberg

9. AMP-Activated Protein Kinase and Cancer Cell Metabolism
Bin Zheng, Lewis C. Cantley

10. The Role of the IGF Axis in Human Malignancy: Evidence from Epidemiological Studies and Tissue Analysis
Julia V. Burnier, Shun Li, Pnina Brodt

11. IGF-I and Insulin Receptor Families in Cancer
Antonino Belfiore, Ira D. Goldfine, Roberta Malaguarnera

12. Insulin Resistance: Clinical Implications for Cancer Treatment and Prevention
Saroj Niraula, Pamela J. Goodwin

Nyckelord: Biomedicine, Cancer Research, Pharmacology/Toxicology