Targeted Drug Strategies for Cancer and Inflammation

1. Biological Role, Properties, and Therapeutic Applications of the Reduced Folate Carrier (RFC-SLC19A1) and the Proton-Coupled Folate Transporter (PCFT-SLC46A1)
Larry H. Matherly, Ndeye Diop-Bove, I. David Goldman

2. Folate Receptors and Therapeutic Applications
Barton A. Kamen

3. Hormonal Control of Folate Receptor Genes
Mesfin Gonit, Marcela D’Alincourt Salazar, Juan Zhang, Hala Elnakat, Suneethi Sivakumaran, Manohar Ratnam

4. Folate Receptor-Targeted Radionuclide Imaging Agents
Cristina Müller, Roger Schibli

5. Folate Receptor Targeted Thymidylate Synthase Inhibitors
Ann L. Jackman, Gerrit Jansen, Matthew Ng

6. Discovery of Novel Antifolate Inhibitors of De Novo Purine Nucleotide Biosynthesis with Selectivity for High Affinity Folate Receptors and the Proton-Coupled Folate Transporter Over the Reduced Folate Carrier for Cellular Entry
Larry H. Matherly, Aleem Gangjee

7. Folate Receptor Targeted Cancer Chemotherapy
Joseph A. Reddy, Christopher P. Leamon

8. Anti-FR Antibody Generation and Engineering: Development of New Therapeutic Tools
Silvana Canevari, Mariangela Figini

9. Folate Receptor Positive Macrophages: Cellular Targets for Imaging and Therapy of Inflammatory and Autoimmune Diseases
Michael J. Hansen, Philip S. Low

10. Targeting Activated Macrophages Via a Functional Folate Receptor for Potential Treatment of Autoimmune/Inflammatory Disorders
Yingjuan Lu, Christopher P. Leamon

11. Liposomes and Polymers in Folate-Targeted Cancer Therapeutics
Alberto Gabizon, Hilary Shmeeda, Hemda Baabur-Cohen, Ronit Satchi-Fainaro

12. Erratum to: Liposomes and Polymers in Folate-Targeted Cancer Therapeutics
Alberto Gabizon, Hilary Shmeeda, Hemda Baabur-Cohen, Ronit Satchi-Fainaro

Nyckelord: Biomedicine, Cancer Research, Pharmacology/Toxicology