Wallach, David
Advances in TNF Family Research
1. Workshop Summary:
Nancy H. Ruddle
2. TNF Conference 2009: Beyond Bones – RANKL/RANK in the Immune System
Andreas Leibbrandt, Josef M. Penninger
3. The Edar Subfamily in Hair and Exocrine Gland Development
Marja L. Mikkola
4. High Endothelial Venule Reporter Mice to Probe Regulation of Lymph Node Vasculature
Kevin L. Bentley, Sharon Stranford, Shan Liao, Rawad M. Mounzer, Frank H. Ruddle, Nancy H. Ruddle
5. Eiger and Wengen: The
Tatsushi Igaki, Hiroshi Kanda, Hideyuki Okano, Tian Xu, Masayuki Miura
6. Workshop Summary:
John Silke, Domagoj Vucic
7. TRAF2 and Cellular IAPs: A Critical Link in TNFR Family Signaling
Domagoj Vucic
8. New Perspectives in TNF-R1-Induced NF-
Ian E. Gentle, John Silke
9. Structural Studies of NEMO and TRAF6: Implications in NF-κB Activation
Hao Wu, Yu-Chih Lo, Qian Yin
10. Modification by Single Ubiquitin Moieties Rather Than Polyubiquitination Is Sufficient for Proteasomal Processing of the p105 NF-
Yelena Kravtsova-Ivantsiv, Shai Cohen, Aaron Ciechanover
11. Selective Binding of Linear Ubiquitin Chains to NEMO in NF-kappaB Activation
Fumiyo Ikeda, Simin Rahighi, Soichi Wakatsuki, Ivan Dikic
12. The Linear Ubiquitin Chain Assembly Complex (LUBAC) Forms Part of the TNF-R1 Signalling Complex and Is Required for Effective TNF-Induced Gene Induction and Prevents TNF-Induced Apoptosis
Christoph H. Emmerich, Anna C. Schmukle, Tobias L. Haas, Björn Gerlach, Stefanie M. Cordier, Eva Rieser, Henning Walczak
13. Temporal Control of TNFα Signaling by Miz1
Anning Lin
14. Large-Scale RNAi Screens to Dissect TNF and NF-
Marie Metzig, Dorothee Nickles, Michael Boutros
15. Pathogenic Role of IL-6 Combined with TNF-α or IL-1 in the Induction of Acute Phase Proteins SAA and CRP in Chronic Inflammatory Diseases
Kazuyuki Yoshizaki
16. Understanding Life and Death at CD95
Carina Pforr, Leo Neumann, Roland Eils, Peter H. Krammer, Inna N. Lavrik
17. Unique Personalities Within the NF-
Deborah Veis Novack
18. Workshop Summary: Functions of the TNF Family in Infectious Disease
Michael Wortzman, Tania H. Watts
19. Role of 4-1BBL and TRAF1 in the CD8 T Cell Response to Influenza Virus and HIV
Tania H. Watts, Gloria H.Y. Lin, Chao Wang, Ann J. McPherson, Laura M. Snell, Laurent Sabbagh
20. Roles of Soluble and Membrane TNF and Related Ligands in Mycobacterial Infections: Effects of Selective and Non-selective TNF Inhibitors During Infection
Irene Garcia, Maria L. Olleros, Valerie F.J. Quesniaux, Muazzam Jacobs, Nasiema Allie, Sergei A. Nedospasov, David E. Szymkowski, Bernhard Ryffel
21. Poxviral TNFRs: Properties and Role in Viral Pathogenesis
Alí Alejo, Sergio M. Pontejo, Antonio Alcami
22. Heme Sensitization to TNF-Mediated Programmed Cell Death
Raffaella Gozzelino, Miguel P. Soares
23. TNF-α and TNFR in Chagas Disease: From Protective Immunity to Pathogenesis of Chronic Cardiomyopathy
Joseli Lannes-Vieira, Isabela Resende Pereira, Nathália Ferreira Vinagre, Lucia Elena Alvarado Arnez
24. Lymphotoxin’s Link to Carcinogenesis: Friend or Foe? From Lymphoid Neogenesis to Hepatocellular Carcinoma and Prostate Cancer
Monika Julia Wolf, Gitta Maria Seleznik, Mathias Heikenwalder
25. Anti-inflammatory Functions of Caspase-8
Akhil Rajput, Tae-Bong Kang, Konstantin Bogdanov, Jin-Chul Kim, Tehila Ben-Moshe, Andrew Kovalenko, David Wallach
26. Endogenous Ligand-Induced Activation of TLR4 in Pre-metastatic Phase Is Both Downstream and Upstream of TNF Signaling
Yoshiro Maru
27. Introductory Words About TL1A/DR3
Stephan R. Targan
28. Introductory Words About TWEAK/Fn14
Linda C. Burkly
29. Insights into TL1A and IBD Pathogenesis
David Q. Shih, Kathrin S. Michelsen, Robert J. Barrett, Eva Biener-Ramanujan, Rivkah Gonsky, Xiaolan Zhang, Stephan R. Targan
30. The Role of TNFRSF25:TNFSF15 in Disease… and Health?
Taylor H. Schreiber, Dietlinde Wolf, Eckhard R. Podack
31. Identification of New Candidates as Mucosal Vaccine Adjuvant in TNF Family Cytokines
Hiroyuki Kayamuro, Yasuo Yoshioka, Yasuhiro Abe, Kazufumi Katayama, Shuhei Arita, Tetsuya Nomura, Tomoaki Yoshikawa, Norio Itoh, Haruhiko Kamada, Shin-ichi Tsunoda, Yasuo Tsutsumi
32. The TWEAK/Fn14 Pathway in Tissue Remodeling: For Better or for Worse
Linda C. Burkly, Taeko Dohi
33. TWEAK and the Kidney: the Dual Role of a Multifunctional Cytokine
Ana Ortiz, M.D. Sanchez-Niño, M.C. Izquierdo, L.M. Blanco-Colio, R. Selgas, M. Ruiz-Ortega, J. Egido, Ana B. Sanz
34. TWEAK and TNF Regulation of Sclerostin: A Novel Pathway for the Regulation of Bone Remodelling
David M. Findlay, Gerald J. Atkins
35. Workshop Summary: Control of Lymphocyte Function and Repertoire by the TNF Superfamily
Carl F. Ware, Jeffrey L. Browning
36. The Canonical and Unconventional Ligands of the Herpesvirus Entry Mediator
Timothy C. Cheung, Carl F. Ware
37. The Lymphotoxin Pathway as a Novel Regulator of Dendritic Cell Function
Leslie Summers deLuca, Jennifer L. Gommerman
38. Involvement of the Cytokine Receptor CD137 in Murine Hematopoiesis
Dongsheng Jiang, Qianqiao Tang, Herbert Schwarz
39. LTBR-Pathway in Sjogren’s Syndrome: CXCL13 Levels and B-cell-Enriched Ectopic Lymphoid Aggregates in NOD Mouse Lacrimal Glands Are Dependent on LTBR
Roy A. Fava, Jeffrey L. Browning, Margaret Gatumu, Kathrine Skarstein, Anne-Isine Bolstad
40. MEK Kinase 1: Kinase Domain Deficiency in Mice Reveals a Role in Orchestrating the Thymus-Dependent Immunity and TNFR Family Signaling
Ewen Gallagher
41. Introduction to the Session “Mechanisms of Pathological and Therapeutic Effects of the TNF Family”
Claude Libert
42. Mechanisms Regulating TNF-Driven Gut and Joint Inflammation
Dirk Elewaut, Peggy Jacques, Lode Melis, Koen Venken
43. Lessons from Anti-TNF Biologics: Infliximab Failure in a TRAPS Family with the T50M Mutation in
Belinda Nedjai, Niamh Quillinan, Robert J. Coughlan, Leigh Church, Michael F. McDermott, Graham A. Hitman, Mark D. Turner
44. Modalities of Experimental TNF Blockade In Vivo: Mouse Models
A.A. Kruglov, A.V. Tumanov, S.I. Grivennikov, Yu.V. Shebzukhov, A.A. Kuchmiy, G.A. Efimov, M.S. Drutskaya, J. Scheller, D.V. Kuprash, Sergei A. Nedospasov
45. Tumor Necrosis Factor-α Signaling via TNFR1/p55 Is Deleterious Whereas TNFR2/p75 Signaling Is Protective in Adult Infarct Myocardium
Raj Kishore, Tengiz Tkebuchava, Sharath P. Sasi, Marcy Silver, Hu-Ya Gilbert, Young-Sup Yoon, Hee-Young Park, Tina Thorne, Douglas W. Losordo, David A. Goukassian
46. TNF-α Regulation of CD38 Expression in Human Airway Smooth Muscle: Role of MAP Kinases and NF-κB
Joseph A. Jude, Reynold A. Panettieri, Timothy F. Walseth, Mathur S. Kannan
47. Functional Consequences of Disease-Associated Mutations in TNFR1 Elucidated by Transcriptome Analysis
Susana L. Rebelo, Paul M. Radford, Susan E. Bainbridge, Ian Todd, Patrick J. Tighe
48. Tumor Necrosis Factor-α and Kidney Function: Experimental Findings in Mice
Dewan S.A. Majid
49. Strategies to Inhibit the Toxicity of Systemic TNF Treatment
Filip Hauwermeiren, Leen Puimège, Sofie Vandevyver, Tom Bogaert, Ineke Vanlaere, Liesbeth Huys, Lien Dejager, Claude Libert
50. Workshop Summary: Introduction to Rational Design of New Means for Therapeutic Modulation of Function of the TNF Family
Klaus Pfizenmaier, David E. Szymkowski
51. Anti-inflammatory Effects of a Novel TNFR1-Selective Antagonistic TNF Mutant on Established Murine Collagen-Induced Arthritis
Yasuhiro Abe, Tetsuya Nomura, Yasuo Yoshioka, Haruhiko Kamada, Shin-ichi Tsunoda, Yasuo Tsutsumi
52. A Proliferation-Inducing Ligand (APRIL): The Development of Antagonistic Agents as Potential Therapeutics and Deciphering the Role of Heparan Sulphate Proteoglycans (HSPGs) in APRIL Signalling
Fiona Kimberley, Marco Guadagnoli, Hans Eenennaam, Jan Paul Medema
53. Genetic Engineering of Death Ligands for Improvement of Therapeutic Activity
Jeannette Gerspach, Britta Schneider, Nicole Müller, Tina Otz, Harald Wajant, Klaus Pfizenmaier
54. Computational Design of TNF Ligand-Based Protein Therapeutics
Almer M. Sloot, Wim J. Quax
55. Workshop Summary: Roles of the TNF Family in Neuronal Development, Function and Pathology
Malú G. Tansey, Tony Wyss-Coray
56. TNF: A Key Neuroinflammatory Mediator of Neurotoxicity and Neurodegeneration in Models of Parkinson’s Disease
Melissa K. McCoy, Kelly A. Ruhn, Armin Blesch, Malú G. Tansey
57. The Contribution of TNFα to Synaptic Plasticity and Nervous System Function
David Stellwagen
58. Intracellular and Intercellular Cross Talk Between NGF and TNF
Yoshinori Takei, Ronald Laskey
59. TNFR2 – Target for Therapeutics Against Neurodegenerative Diseases?
Ingrid M. Nijholt, Ivica Granic, Paul G.M. Luiten, Ulrich L.M. Eisel
60. A Role for Neuronal NF-κB in Suppressing Neuroinflammation and Promoting Neuroprotection in the CNS
Mary Emmanouil, Era Taoufik, Vivian Tseveleki, Sotiris-Spyros Vamvakas, Lesley Probert
61. Workshop Summary: Cell Death Mechanisms Controlled by the TNF Family
John E. Eriksson, Peter Vandenabeele
62. A RNA Interference Screen Identifies RIP3 as an Essential Inducer of TNF-Induced Programmed Necrosis
YoungSik Cho, Sreerupa Challa, Francis Ka-Ming Chan
63. The Extracellular Matrix Protein CCN1 Dictates TNFα and FasL Cytotoxicity In Vivo
Chih-Chiun Chen, Vladislava Juric, Lester F. Lau
64. Compartmentalization of TNF-Receptor 1 Signaling: TNF-R1-Associated Caspase-8 Mediates Activation of Acid Sphingomyelinase in Late Endosomes
Uwe Bertsch, Bärbel Edelmann, Vladimir Tchikov, Supandi Winoto-Morbach, Stefan Schütze
65. TNF/TNF Receptor 1-Mediated Apoptosis in Hepatocytes
Hyun-Ae Eum, Timothy R. Billiar
66. Regulation of Cell Death by c-FLIP Phosphorylation
Tomoko Asaoka, Aura Kaunisto, John E. Eriksson
Nyckelord: Biomedicine, Immunology, Microbiology, Biomedicine general
- Författare
- Wallach, David
- Kovalenko, Andrew
- Feldmann, Marc
- Utgivare
- Springer
- Utgivningsår
- 2011
- Språk
- en
- Utgåva
- 1
- Serie
- Advances in Experimental Medicine and Biology
- Sidantal
- 36 sidor
- Kategori
- Hälsa, skönhet, mode
- Format
- E-bok
- eISBN (PDF)
- 9781441966124