Vascular Disruptive Agents for the Treatment of Cancer

1. Development of Vascular Disrupting Agents
Graeme J. Dougherty, David J. Chaplin

2. The Discovery and Characterisation of Tumour Endothelial Markers
Dario Neri, Roy Bicknell

3. The Use of Animal Models in the Assessment of Tumour Vascular Disrupting Agents (VDAs)
R. Barbara Pedley, Gillian M. Tozer

4. Combination Therapy with Chemotherapy and VDAs
Giulia Taraboletti, Katiuscia Bonezzi, Raffaella Giavazzi

5. Lessons from Animal Imaging in Preclinical Models
Lesley D. McPhail, Simon P. Robinson

6. Combining Antiangiogenic Drugs with Vascular Disrupting Agents Rationale and Mechanisms of Action
Yuval Shaked, Paul Nathan, Laura G. M. Daenen, Robert S. Kerbel

7. MRI to Assess Vascular Disruptive Agents
Martin Zweifel, Anwar R. Padhani

8. Contrast Ultrasound in Imaging Tumor Angiogenesis
Grzegorz Korpanty, Rolf A. Brekken

9. The Clinical Development of Tubulin Binding Vascular Disrupting Agents
Martin Zweifel, Gordon Rustin

10. ASA404 (DMXAA): New Concepts in Tumour Vascular Targeting Therapy
Bruce C. Baguley

11. Vascular Disruptive Agents in Combination with Radiotherapy
Henry C. Mandeville, Peter J. Hoskin

Nyckelord: Biomedicine, Cancer Research, Pharmacology/Toxicology