Retinal Degenerative Diseases

1. Analysis of Genes Differentially Expressed During Retinal Degeneration in Three Mouse Models
Yogita Kanan, Michael Centola, Frank Bart, Muayyad R. Al-Ubaidi

2. Regulation of Angiogenesis by Macrophages
Rajendra S. Apte

3. Protein Kinase C Regulates Rod Photoreceptor Differentiation Through Modulation of STAT3 Signaling
Carolina Pinzon-Guzman, Samuel Shaomin Zhang, Colin J. Barnstable

4. Pigment Epithelium-derived Factor Receptor (PEDF-R): A Plasma Membrane-linked Phospholipase with PEDF Binding Affinity
Preeti Subramanian, Patricia M. Notario, S. Patricia Becerra

5. The Function of Oligomerization-Incompetent RDS in Rods
Dibyendu Chakraborty, Shannon M. Conley, Steven J. Fliesler, Muna I. Naash

6. The Association Between Telomere Length and Sensitivity to Apoptosis of HUVEC
Ji Zhang, Chen Hui, Liu Su, Wu Xiaoyun, Huang Xi, Fan Yingchuan

7. Photoreceptor Guanylate Cyclases and cGMP Phosphodiesterases in Zebrafish
Ross F. Collery, Breandán N. Kennedy

8. RDS in Cones Does Not Interact with the Beta Subunit of the Cyclic Nucleotide Gated Channel
Shannon M. Conley, Xi-Qin Ding, Muna I. Naash

9. Increased Expression of TGF-β1 and Smad 4 on Oxygen-Induced Retinopathy in Neonatal Mice
Fan Yingchuan, Lei Chuntao, Chen Hui, Hu Jianbin

10. ZBED4, A Novel Retinal Protein Expressed in Cones and Müller Cells
Debora B. Farber, V. P. Theendakara, N. B. Akhmedov, M. Saghizadeh

11. Tubby-Like Protein 1 (Tulp1) Is Required for Normal Photoreceptor Synaptic Development
Gregory H. Grossman, Gayle J. T. Pauer, Umadevi Narendra, Stephanie A. Hagstrom

12. Growth-Associated Protein43 (GAP43) Is a Biochemical Marker for the Whole Period of Fish Optic Nerve Regeneration
Manabu Kaneda, Mikiko Nagashima, Kazuhiro Mawatari, Tomoya Nunome, Kenichiro Muramoto, Kayo Sugitani, Satoru Kato

13. Multiprotein Complexes of Retinitis Pigmentosa GTPase Regulator (RPGR), a Ciliary Protein Mutated in X-Linked Retinitis Pigmentosa (XLRP)
Carlos Murga-Zamalloa, Anand Swaroop, Hemant Khanna

14. Misfolded Proteins and Retinal Dystrophies
Jonathan H. Lin, Matthew M. LaVail

15. Neural Retina and MerTK-Independent Apical Polarity of αvβ5 Integrin Receptors in the Retinal Pigment Epithelium
Mallika Mallavarapu, Silvia C. Finnemann

16. Mertk in Daily Retinal Phagocytosis: A History in the Making
Emeline F. Nandrot, Eric M. Dufour

17. The Interphotoreceptor Retinoid Binding (IRBP) Is Essential for Normal Retinoid Processing in Cone Photoreceptors
Ryan O. Parker, Rosalie K. Crouch

18. Aseptic Injury to Epithelial Cells Alters Cell Surface Complement Regulation in a Tissue Specific Fashion
Joshua M. Thurman, Brandon Renner, Kannan Kunchithapautham, V. Michael Holers, Bärbel Rohrer

19. Role of Metalloproteases in Retinal Degeneration Induced by Violet and Blue Light
C. Sanchez-Ramos, J. A. Vega, M.E. del Valle, A. Fernandez-Balbuena, C. Bonnin-Arias, J. M. Benitez-del Castillo

20. Mitochondrial Decay and Impairment of Antioxidant Defenses in Aging RPE Cells
Yuan He, Joyce Tombran-Tink

21. Ciliary Transport of Opsin
Deepti Trivedi, David S. Williams

22. Effect of Hesperidin on Expression of Inducible Nitric Oxide Synthase in Cultured Rabbit Retinal Pigment Epithelial Cells
Luo Xiaoting, Zeng Xiangyun, Li Shumei, Dong Minghua, Xiong Liang

23. Profiling MicroRNAs Differentially Expressed in Rabbit Retina
Naihong Yan, Ke Ma, Jia Ma, Wei Chen, Yun Wang, Guiqun Cao, Dominic Man-Kit Lam, Xuyang Liu

24. Unexpected Transcriptional Activity of the Human VMD2 Promoter in Retinal Development
Meili Zhu, Lixin Zheng, Yumi Ueki, John D. Ash, Yun-Zheng Le

25. Microarray Analysis of Hyperoxia Stressed Mouse Retina: Differential Gene Expression in the Inferior and Superior Region
Yuan Zhu, Riccardo Natoli, Krisztina Valter, Jonathan Stone

26. Photoreceptor Sensory Cilia and Inherited Retinal Degeneration
Qin Liu, Qi Zhang, Eric A. Pierce

27. Role of Elovl4 Protein in the Biosynthesis of Docosahexaenoic Acid
Martin-Paul Agbaga, Richard S. Brush, Md Nawajes A. Mandal, Michael H. Elliott, Muayyad R. Al-Ubaidi, Robert E. Anderson

28. Molecular Pathogenesis of Achromatopsia Associated with Mutations in the Cone Cyclic Nucleotide-Gated Channel CNGA3 Subunit
Xi-Qin Ding, J. Browning Fitzgerald, Alexander B. Quiambao, Cynthia S. Harry, Anna P. Malykhina

29. Mutation Spectra in Autosomal Dominant and Recessive Retinitis Pigmentosa in Northern Sweden
Irina Golovleva, Linda Köhn, Marie Burstedt, Stephen Daiger, Ola Sandgren

30. 1 Rhodopsin Mutations in Congenital Night Blindness
Suzanne D. McAlear, Timothy W. Kraft, Alecia K. Gross

31. GCAP1 Mutations Associated with Autosomal Dominant Cone Dystrophy
Li Jiang, Wolfgang Baehr

32. Genotypic Analysis of X-linked Retinoschisis in Western Australia
Tina Lamey, Sarina Laurin, Enid Chelva, John Roach

33. Mutation Frequency of IMPDH1 Gene of Han Population in Ganzhou City
Li Shumei, Luo Xiaoting, Zeng Xiangyun, Hu Liqun, Xiong Liang, Li Sisi

34. Reversible and Size-Selective Opening of the Inner Blood-Retina Barrier: A Novel Therapeutic Strategy
Matthew Campbell, Anh Thi Hong Nguyen, Anna-Sophia Kiang, Lawrence Tam, Paul F. Kenna, Sorcha Ni Dhubhghaill, Marian Humphries, G. Jane Farrar, Peter Humphries

35. Spectral Domain Optical Coherence Tomography and Adaptive Optics: Imaging Photoreceptor Layer Morphology to Interpret Preclinical Phenotypes
Jungtae Rha, Adam M. Dubis, Melissa Wagner-Schuman, Diane M. Tait, Pooja Godara, Brett Schroeder, Kimberly Stepien, Joseph Carroll

36. Pharmacological Manipulation of Rhodopsin Retinitis Pigmentosa
Hugo F. Mendes, Raffaella Zaccarini, Michael E. Cheetham

37. Targeted High-Throughput DNA Sequencing for Gene Discovery in Retinitis Pigmentosa
Stephen P. Daiger, Lori S. Sullivan, Sara J. Bowne, David G. Birch, John R. Heckenlively, Eric A. Pierce, George M. Weinstock

38. Advances in Imaging of Stargardt Disease
Y. Chen, A. Roorda, J.L. Duncan

39. Protamine Sulfate Downregulates Vascular Endothelial Growth Factor (VEGF) Expression and Inhibits VEGF and Its Receptor Binding in Vitro
Jianbin Hu, Chao Qu, Yufeng Yu, Ma Ping, Dong Wei, Dong Dandan

40. Computer-Assisted Semi-Quantitative Analysis of Mouse Choroidal Density
Yun-Zheng Le

41. Thioredoxins 1 and 2 Protect Retinal Ganglion Cells from Pharmacologically Induced Oxidative Stress, Optic Nerve Transection and Ocular Hypertension
Yasunari Munemasa, Jacky M. K. Kwong, Seok H. Kim, Jae H. Ahn, Joseph Caprioli, Natik Piri

42. Near-Infrared Light Protect the Photoreceptor from Light-Induced Damage in Rats
Chao Qu, Wei Cao, Yingchuan Fan, Ying Lin

43. BDNF Improves the Efficacy ERG Amplitude Maintenance by Transplantation of Retinal Stem Cells in RCS Rats
Chunyu Tian, Chuan Chuang Weng, Zheng Qin Yin

44. The Role of Purinergic Receptors in Retinal Function and Disease
Michelle M. Ward, Theresa Puthussery, Kirstan A. Vessey, Erica L. Fletcher

45. Fundus Autofluorescence Imaging in Age-Related Macular Degeneration and Geographic Atrophy
Srilaxmi Bearelly, Scott W. Cousins

46. Endoplasmic Reticulum Stress as a Primary Pathogenic Mechanism Leading to Age-Related Macular Degeneration
Richard T. Libby, Douglas B. Gould

47. Proteomic and Genomic Biomarkers for Age-Related Macular Degeneration
Jiayin Gu, Gayle J.T. Pauer, Xiuzhen Yue, Umadevi Narendra, Gwen M. Sturgill, James Bena, Xiaorong Gu, Neal S. Peachey, Robert G. Salomon, Stephanie A. Hagstrom, John W. Crabb

48. Impaired Intracellular Signaling May Allow Up-Regulation of CTGF-Synthesis and Secondary Peri-Retinal Fibrosis in Human Retinal Pigment Epithelial Cells from Patients with Age-Related Macular Degeneration
Piyush C. Kothary, Jaya Badhwar, Christina Weng, Monte A. Del Monte

49. PPAR Nuclear Receptors and Altered RPE Lipid Metabolism in Age-Related Macular Degeneration
Goldis Malek, Peng Hu, Albert Wielgus, Mary Dwyer, Scott Cousins

50. The Pathophysiology of Cigarette Smoking and Age-Related Macular Degeneration
S.S. Ni Dhubhghaill, M.T. Cahill, M. Campbell, L. Cassidy, M.M. Humphries, P. Humphries

51. Oxidative Stress and the Ubiquitin Proteolytic System in Age-Related Macular Degeneration
Scott M. Plafker

52. Slit-Robo Signaling in Ocular Angiogenesis
Haoyu Chen, Mingzhi Zhang, Shibo Tang, Nyall R. London, Dean Y. Li, Kang Zhang

53. Evaluation of Retinal Degeneration in P27KIP1 Null Mouse
Yumi Tokita-Ishikawa, Ryosuke Wakusawa, Toshiaki Abe

54. Differences in Photoreceptor Sensitivity to Oxygen Stress Between Long Evans and Sprague-Dawley Rats
Vicki Chrysostomou, Jonathan Stone, Krisztina Valter

55. Retinal Degeneration in a Rat Model of Smith-Lemli-Opitz Syndrome: Thinking Beyond Cholesterol Deficiency
Steven J. Fliesler

56. Do Calcium Channel Blockers Rescue Dying Photoreceptors in the Pde6b

rd1

Mouse?

Peter Barabas, Carolee Cutler Peck, David Krizaj

57. Effect of PBNA on the NO Content and NOS Activity in Ischemia/Reperfusion Injury in the Rat Retina
Liangdong Li, Zhihua Huang, Hai Xiao, Xigui Chen, Jing Zeng

58. Recent Insights into the Mechanisms Underlying Light-Dependent Retinal Degeneration from X. Laevis Models of Retinitis Pigmentosa
Orson L. Moritz, Beatrice M. Tam

59. A Hypoplastic Retinal Lamination in the Purpurin Knock Down Embryo in Zebrafish
Mikiko Nagashima, Junichi Saito, Kazuhiro Mawatari, Yusuke Mori, Toru Matsukawa, Yoshiki Koriyama, Satoru Kato

60. Functional Changes in Inner Retinal Neurons in Animal Models of Photoreceptor Degeneration
Theresa Puthussery, W. Rowland Taylor

61. Photoreceptor Cell Degeneration in Abcr
–/– Mice
Li Wu, Taka Nagasaki, Janet R. Sparrow

62. Investigating the Mechanism of Disease in the RP10 Form of Retinitis Pigmentosa
Catherine J. Spellicy, Dong Xu, Garrett Cobb, Lizbeth Hedstrom, Sara J. Bowne, Lori S. Sullivan, Stephen P. Daiger

63. Congenital Stationary Night Blindness in Mice – A Tale of Two Cacna1f Mutants
N. Lodha, S. Bonfield, N.C. Orton, C.J. Doering, J.E. McRory, S.C. Mema, R. Rehak, Y. Sauvé, R. Tobias, W.K. Stell, N.T. Bech-Hansen

64. Protection of Photoreceptors in a Mouse Model of RP10
Lawrence C.S. Tam, Anna-Sophia Kiang, Naomi Chadderton, Paul F. Kenna, Matthew Campbell, Marian M. Humphries, G. Jane Farrar, Pete Humphries

65. Correlation Between Tissue Docosahexaenoic Acid Levels and Susceptibility to Light-Induced Retinal Degeneration
Masaki Tanito, Richard S. Brush, Michael H. Elliott, Lea D. Wicker, Kimberly R. Henry, Robert E. Anderson

66. Activation of Müller Cells Occurs During Retinal Degeneration in RCS Rats
Tong Tao Zhao, Chun Yu Tian, Zheng Qin Yin

67. Effect of 3′-Daidzein Sulfonic Sodium on the Anti-oxidation of Retinal Ischemia/Reperfusion Injury in Rats
Huang Zhihua, Li Liangdong, Li Xiao, Cheng Fang, Zeng Jing

68. Structural and Functional Phenotyping in the Cone-Specific Photoreceptor Function Loss 1 (cpfl1) Mouse Mutant – A Model of Cone Dystrophies
M. Dominik Fischer, Naoyuki Tanimoto, Susanne C. Beck, Gesine Huber, Karin Schaeferhoff, Stylianos Michalakis, Olaf Riess, Bernd Wissinger, Martin Biel, Michael Bonin, Mathias W. Seeliger

69. The Differential Role of Jak/Stat Signaling in Retinal Degeneration
C. Lange, M. Thiersch, M. Samardzija, C. Grimm

70. Gene Therapy in the Retinal Degeneration Slow Model of Retinitis Pigmentosa
Xue Cai, Shannon M. Conley, Muna I. Naash

71. PEDF Promotes Retinal Neurosphere Formation and Expansion In Vitro
Anna Marzo, Claudia Aruta, Valeria Marigo

72. A Multi-Stage Color Model Revisited: Implications for a Gene Therapy Cure for Red-Green Colorblindness
Katherine Mancuso, Matthew C. Mauck, James A. Kuchenbecker, Maureen Neitz, Jay Neitz

73. Achromatopsia as a Potential Candidate for Gene Therapy
Ji-Jing Pang, John Alexander, Bo Lei, Wentao Deng, Keqing Zhang, Qiuhong Li, Bo Chang, William W. Hauswirth

74. Function and Mechanism of CNTF/LIF Signaling in Retinogenesis
Kun Do Rhee, Xian-Jie Yang

75. gp130 Activation in Müller Cells is Not Essential for Photoreceptor Protection from Light Damage
Yumi Ueki, Srinivas Chollangi, Yun-Zheng Le, John D. Ash

76. Neuroprotectin D1 Modulates the Induction of Pro-Inflammatory Signaling and Promotes Retinal Pigment Epithelial Cell Survival DuringOxidative Stress
Jorgelina M. Calandria, Nicolas G. Bazan

77. Adeno-Associated Virus Serotype-9 Mediated Retinal Outer Plexiform Layer Transduction is Mainly Through the Photoreceptors
Bo Lei, Keqing Zhang, Yongping Yue, Arkasubhra Ghosh, Dongsheng Duan

Nyckelord: Medicine & Public Health, Ophthalmology