Macromolecular Anticancer Therapeutics

1. Classification of Anticancer Drugs Based on Therapeutic Targets
Enrique Espinosa, César Gómez Raposo

2. Signal Transduction Pathways as Therapeutic Targets in Cancer Therapy
Michele Milella, Ludovica Ciuffreda, Emilio Bria

3. HPMA-Anticancer Drug Conjugates
B. Rihova, O. Hovorka, L. Kovar, M. Kovar, T. Mrkvan, M. Sirova, V. Subr, K. Ulbrich

4. Poly-l-Glutamic Acid Anti-cancer Drug Conjugates
Jack W. Singer, Marc McKennon, Gabriella Pezzoni, Stefano di Giovine, Mara Cassin, Paola Feudis, Cecilia Allievi, Patrizia Angiuli, Marco Natangelo, Enrico Vezzali, Stefano Fazioni

5. Polysaccharide-Based Anticancer Prodrugs
Paolo Caliceti, Stefano Salmaso, Sara Bersani

6. PEG–Anticancer Drugs
Francesca Cateni, Marina Zacchigna

7. Poly(ethylene glycol)-Protein, Peptide, and Enzyme Conjugates
F.M. Veronese, G. Pasut, S. Drioli, G.M. Bonora

8. Lipid-Based Anticancer Prodrugs
L. Harivardhan Reddy, Patrick Couvreur

9. Antibody–Cytotoxic Compound Conjugates for Oncology
Carol A. Vater, Victor S. Goldmacher

10. Immunoconjugate Anticancer Therapeutics
Serengulam V. Govindan, David M. Goldenberg

11. Antibody-Directed Enzyme Prodrug Therapy (ADEPT) for Cancer
Surinder K. Sharma, Kenneth D. Bagshawe

12. EGFR-Directed Monoclonal Antibodies
Roberto Bianco, Teresa Gelardi, Sonia Garofalo, Roberta Rosa, Giampaolo Tortora

13. The Biology of the HER Family and Her2/neu Directed-Antibody Therapy
Jennifer K. Litton, Gabriel N. Hortobagyi

14. Anti-Vascular Endothelial Growth Factor Monoclonal Antibodies
Ernest S. Han, Bradley J. Monk

15. Monoclonal Antibody Therapy for Hematologic Malignancies
Kenneth A. Foon, Michael Boyiadzis, Samuel A. Jacobs

16. Anticancer Oligonucleotides
Anne Laure Ramon, Claude Malvy

17. New Molecular Therapeutic Interventions: The Case of Breast Cancers
Véronique Marsaud, Jack-Michel Renoir

Nyckelord: Biomedicine, Cancer Research, Pharmacology/Toxicology