Therapeutic Resistance to Anti-Hormonal Drugs in Breast Cancer

1. Experimental Endocrine Resistance: Concepts and Strategies
Robert I. Nicholson, Iain R. Hutcheson, Stephen Hiscox, Kathy M. Taylor, Julia M.W. Gee

2. Transcriptional Coactivators and Corepressors in Endocrine Response and Resistance in Breast Cancer
Simak Ali

3. The Re-Expression of Estrogen Receptor in Estrogen
Receptor-Negative Breast Cancer and Restoration of Anti-Estrogen
Responses
Jill Bayliss, Amy Hilger, Prakash Vishnu, Kathleen Diehl, Dorraya El-Ashry

4. The Dark Side of Antihormonal Action in Breast Cancer
Julia M.W. Gee, Andrew Stone, Richard A. McClelland, Stephen Hiscox, Iain R. Hutcheson, Nicola J. Jordan, Heidi M. Fiegl, Martin Widschwendter, Victoria E. Shaw, Denise Barrow, Robert I. Nicholson

5. Influence of the Tumour Microenvironment
Rosemary A. Walker

6. Are Stem-Like Cells Responsible for Resistance to Therapy in Breast Cancer?
Ciara S. O’Brien, Gillian Farnie, Sacha J. Howell, Robert B. Clarke

7. HSP90 Inhibition as an Anticancer Strategy: Novel Approaches and Future Directions
Marissa V. Powers, Paul Workman

8. Adverse Features of Acquired Antihormone Resistance and Their Targeting
Stephen Hiscox, Nicola Jordan, Liam Morgan, Chris Smith, Lindy Goddard, Julia M.W. Gee, Robert I. Nicholson

9. Identifying Modifiers of Tamoxifen Sensitivity Using High-Throughput Genetic and Chemical Screens
Elizabeth Iorns, Christopher J. Lord, Alan Ashworth

10. Endocrine Resistance in Breast Cancer- Where Are We NowWith Intelligent Combination Therapies?
Stephen R.D. Johnston

Nyckelord: MEDICAL / Public Health MED078000