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Foundation, Novartis

The hERG Cardiac Potassium Channel: Structure, Function and Long QT Syndrome, Novartis Foundation Symposium

Foundation, Novartis - The hERG Cardiac Potassium Channel: Structure, Function and Long QT Syndrome, Novartis Foundation Symposium, e-bok

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ISBN: 9780470021415
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This book draws together contributions from basic, pharmaceutical and clinical sciences aimed at a better understanding of the structure and function of hERG and the molecular basis for compound binding. 

It features regulatory authority perspectives on preferred preclinical test systems and includes topics on hERG channel gating, regulation of functional expression, pharmacological properties of hERG/IKr channels, drug-induced long QT syndrome and preclinical evaluation and regulatory recommendations for assessing QT prolongation risks. 

Better understanding of the role of the hERG channel in drug-induced cardiac arrhythmias should ultimately lead to the development of important, new and safer medicines.

Nyckelord: SCIENCE / Life Sciences / Biochemistry SCI007000

Författare
Utgivare
John Wiley and Sons, Inc.
Utgivningsår
2005
Språk
en
Utgåva
1
Serie
Novartis Foundation Symposia
Sidantal
308 sidor
Kategori
Naturvetenskaper
Format
E-bok
eISBN (PDF)
9780470021415
Tryckt ISBN
9780470021408

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