Anderson, Robert E.
Recent Advances in Retinal Degeneration
Part I.Keynote Lectures
1. Curing Blindness with Stem Cells: Hope, Reality, and Challenges
Ruben Adler
2. Retinal Degenerations: Planning for the Future
Eliot L. Berson
Part II.Neuroprotection
3. Neurotrophins Induce Neuroprotective Signaling in the Retinal Pigment Epithelial Cell by Activating the Synthesis of the Anti-inflammatory and Anti-apoptotic Neuroprotectin D1
Nicolas G. Bazan
4. On the Role of CNTF as a Potential Therapy for Retinal Degeneration: Dr. Jekyll or Mr. Hyde?
William A. Beltran
5. Nanoceria Particles Prevent ROI-Induced Blindness
Junping Chen, Swanand Patil, Sudipta Seal, James F. McGinnis
6. An in-vivo Assay to Identify Compounds Protective Against Light Induced Apoptosis
Yogita Kanan, Anne Kasus Jacobi, Kjell Sawyer, David S. Mannel, Joyce Tombran Tink, Muayyad R. Al-Ubaidi
7. Role of BCL-XL in Photoreceptor Survival
Yun-Zheng Le, Lixin Zheng, Yuwei Le, Edmund B. Rucker, Robert E. Anderson
8. The Hypoxic Transcriptome of the Retina: Identification of Factors with Potential Neuroprotective Activity
Markus Thiersch, Wolfgang Raffelsberger, Enrico Frigg, Marijana Samardzija, Patricia Blank, Olivier Poch, Christian Grimm
Part III.Gene Therapy and Neuroprotection
9. Lentiviral Gene Transfer-Mediated Cone Vision Restoration in RPE65 Knockout Mice
Alexis-Pierre Bemelmans, Corinne Kostic, Maité Cachafeiro, Sylvain V. Crippa, Dana Wanner, Meriem Tekaya, Andreas Wenzel, Yvan Arsenijevic
10. In vitro Analysis of Ribozyme-mediated Knockdown of an ADRP Associated Rhodopsin Mutation
Dibyendu Chakraborty, Patrick Whalen, Alfred S. Lewin, Muna I. Naash
11. Gene Therapy for Mouse Models of ADRP
Marina S. Gorbatyuk, William W. Hauswirth, Alfred S. Lewin
12. Development of Viral Vectors with Optimal Transgene Expression for Ocular Gene Therapies
Takao Hashimoto
13. Adeno-Associated Viral Vectors and the Retina
John J. Alexander, William W. Hauswirth
14. Genetic Supplementation of RDS Alleviates a Loss-of-function Phenotype in C214S Model of Retinitis Pigmentosa
May Nour, Steven J. Fliesler, Muna I. Naash
15. Morphological Aspects Related to Long-term Functional Improvement of the Retina in the 4 Years Following rAAV-mediated Gene Transfer in the RPE65 Null Mutation Dog
Kristina Narfström, Mathias Seeliger, Chooi-May Lai, Vaegan, Martin Katz, Elizabeth P. Rakoczy, Charlotte Remé
16. Virus-mediated Gene Delivery to Neuronal Progenitors
Tonia S. Rex
Part IV.Animal Models of Retinal Degeneration
17. Loss of Visual and Retinal Function in Light-stressed Mice
Drew Everhart, Ana Stachowiak, Yumiko Umino, Robert Barlow
18. ERG Responses and Microarray Analysis of Gene Expression in a Multifactorial Murine Model of Age-Related Retinal Degeneration
Goldis Malek, Jeffery A. Jamison, Brian Mace, Patrick Sullivan, Catherine Bowes Rickman
19. Oxygen Supply and Retinal Function: Insights from a Transgenic Animal Model
Edda Fahl, Max Gassmann, Christian Grimm, Mathias W. Seeliger
20. Characterization of Gene Expression Profiles of Normal Canine Retina and Brain Using a Retinal cDNA Microarray
Gerardo L. Paez, Barbara Zangerl, Kimberly Sellers, Gregory M. Acland, Gustavo D. Aguirre
21. Toward a Higher Fidelity Model of AMD
Brian J. Raisler, Miho Nozaki, Judit Baffi, William W. Hauswirth, Jayakrishna Ambati
22. The Potential of Ambient Light Restriction to Restore Function to the Degenerating P23H-3 Rat Retina
Krisztina Valter, Diana K. Kirk, Jonathan Stone
Part V.Molecular Genetics and Candidate Genes
23. Mutations in Known Genes Account for 58% of Autosomal Dominant Retinitis Pigmentosa (adRP)
Stephen P. Daiger, Lori S. Sullivan, Anisa I. Gire, David G. Birch, John R. Heckenlively, Sara J. Bowne
24. Genetics of Age-related Macular Degeneration
Albert O. Edwards
25. Retinal Phenotype of an X-Linked Pseudo-usher Syndrome in Association with the G173R Mutation in the
Alessandro Iannaccone, Mohammad I. Othman, April D. Cantrell, Barbara J. Jennings, Kari Branham, Anand Swaroop
26. Mutation in the PYK2-Binding Domain of PITPNM3 Causes Autosomal Dominant Cone Dystrophy (CORD5) in Two Swedish Families
Linda Köhn, Konstantin Kadzhaev, Marie S.I. Burstedt, Susann Haraldsson, Ola Sandgren, Irina Golovleva
27. Identification and Characterization of Genes Expressed in Cone Photoreceptors
Mehrnoosh Saghizadeh, Novrouz B. Akhmedov, Debora B. Farber
28. Clinical and Genetic Characterization of a Chinese Family with CSNB1
Ruifang Sui, Fengrong Li, Jialiang Zhao, Ruxin Jiang
29. 10q26 Is Associated with Increased Risk of Age-Related Macular Degeneration in the Utah Population
D. Joshua Cameron, Zhenglin Yang, Zhongzhong Tong, Yu Zhao, Alissa Praggastis, Eric Brinton, Jennifer Harmon, Yali Chen, Erik Pearson, Paul S. Bernstein, Gregory Brinton, Xi Li, Adam Jorgensen, Sara Schneider, Daniel Gibbs, Haoyu Chen, Changguan Wang, Kimberly Howes, Nicola J. Camp, Kang Zhang
Part VI.Diagnostic, Clinical, Cytopathological and Physiologic Aspects of Retinal Degeneration
30. Carboxyethylpyrrole Adducts, Age-related Macular Degeneration and Neovascularization
Kutralanathan Renganathan, Quteba Ebrahem, Amit Vasanji, Xiaorong Gu, Liang Lu, Jonathan Sears, Robert G. Salomon, Bela Anand-Apte, John W. Crabb
31. A Possible Impaired Signaling Mechanism in Human Retinal Pigment Epithelial Cells from Patients with Macular Degeneration
Piyush C. Kothary, Monte A. Del Monte
32. Expression and Cell Compartmentalization of EFEMP1, a Protein Associated with
Adam Kundzewicz, Francis Munier, Jean-Marc Matter
33. Role of ELOVL4 in Fatty Acid Metabolism
Vidyullatha Vasireddy, Majchrzak Sharon, Norman Salem, Radha Ayyagari
34. Organization and Molecular Interactions of Retinoschisin in Photoreceptors
Camasamudram Vijayasarathy, Yuichiro Takada, Yong Zeng, Ronald A. Bush, Paul A. Sieving
Part VII.Basic Science Underlying Retinal Degeneration
35. Proteomics Profiling of the Cone Photoreceptor Cell Line, 661W
Muayyad R. Al-Ubaidi, Hiroyuki Matsumoto, Sadamu Kurono, Anil Singh
36. ?-Secretase Regulates VEGFR-1 Signalling in Vascular Endothelium and RPE
Michael E. Boulton, Jun Cai, Maria B. Grant, Yadan Zhang
37. Analysis of the Rate of Disk Membrane Digestion by Cultured RPE Cells
Tanja Diemer, Daniel Gibbs, David S. Williams
38. Functional Expression of Cone Cyclic Nucleotide-Gated Channel in Cone Photoreceptor-Derived 661W Cells
J. Browning Fitzgerald, Anna P. Malykhina, Muayyad R. Al-Ubaidi, Xi-Qin Ding
39. Phosphorylation of Caveolin-1 in Bovine Rod Outer Segments in vitro by an Endogenous Tyrosine Kinase
Michael H. Elliott, Abboud J. Ghalayini
40. Regulation of Neurotrophin Expression and Activity in the Retina
Abigail S. Hackam
41. Involvement of Guanylate Cyclases in Transport of Photoreceptor Peripheral Membrane Proteins
Sukanya Karan, Jeanne M. Frederick, Wolfgang Baehr
42. Rod Progenitor Cells in the Mature Zebrafish Retina
Ann C. Morris, Tamera Scholz, James M. Fadool
43. avß5 Integrin Receptors at the Apical Surface of the RPE: One Receptor, Two Functions
Emeline F. Nandrot, Yongen Chang, Silvia C. Finnemann
44. Implantation of Mouse Eyes with a Subretinal Microphotodiode Array
Machelle T. Pardue, Tiffany A. Walker, Amanda E. Faulkner, Moon K. Kim, Christopher M. Bonner, George Y. McLean
45. Variation in the Electroretinogram of C57BL/6 Substrains of Mouse
Alison L. Reynolds, G. Jane Farrar, Pete Humphries, Paul F. Kenna
46. A2E, A Pigment of RPE Lipofuscin, is Generated from the Precursor, A2PE by a Lysosomal Enzyme Activity
Janet R. Sparrow, So Ra Kim, Ana M. Cuervo, Urmi Bandhyopadhyayand
47. Endothelin Receptors: Do They Have a Role in Retinal Degeneration?
Vanesa Torbidoni, María Iribarne, Angela M. Suburo
48. CNTF Negatively Regulates the Phototransduction Machinery in Rod Photoreceptors: Implication for Light-Induced Photostasis Plasticity
Rong Wen, Ying Song, Yun Liu, Yiwen Li, Lian Zhao, Alan M. Laties
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Nyckelord: MEDICAL / Public Health MED078000
- Författare
- Anderson, Robert E.
- Hollyfield, Joe G.
- Vail, Matthew M. La
- Utgivare
- Springer
- Utgivningsår
- 2008
- Språk
- en
- Utgåva
- 1
- Kategori
- Hälsa, skönhet, mode
- Format
- E-bok
- eISBN (PDF)
- 9780387749044