Design and Analysis of Vaccine Studies

1. Introduction and Examples
M. Elizabeth Halloran, Ira M. Longini, Claudio J. Struchiner

2. Overview of Vaccine Effects and Study Designs
M. Elizabeth Halloran, Ira M. Longini, Claudio J. Struchiner

3. Immunology and Early Phase Trials
M. Elizabeth Halloran, Ira M. Longini, Claudio J. Struchiner

4. Binomial and Stochastic Transmission Models
M. Elizabeth Halloran, Ira M. Longini, Claudio J. Struchiner

5.
R
0 and Deterministic Models
M. Elizabeth Halloran, Ira M. Longini, Claudio J. Struchiner

6. Evaluating Protective Effects of Vaccination
M. Elizabeth Halloran, Ira M. Longini, Claudio J. Struchiner

7. Modes of Action and Time-Varying VE
S


M. Elizabeth Halloran, Ira M. Longini, Claudio J. Struchiner

8. Further Evaluation of Protective Effects
M. Elizabeth Halloran, Ira M. Longini, Claudio J. Struchiner

9. Vaccine Effects on Post-Infection Outcomes
M. Elizabeth Halloran, Ira M. Longini, Claudio J. Struchiner

10. Household-Based Studies
M. Elizabeth Halloran, Ira M. Longini, Claudio J. Struchiner

11. Analysis of Households in Communities
M. Elizabeth Halloran, Ira M. Longini, Claudio J. Struchiner

12. Analysis of Independent Households
M. Elizabeth Halloran, Ira M. Longini, Claudio J. Struchiner

13. Assessing Indirect, Total, and Overall Effects
M. Elizabeth Halloran, Ira M. Longini, Claudio J. Struchiner

14. Randomization and Baseline Transmission
M. Elizabeth Halloran, Ira M. Longini, Claudio J. Struchiner

15. Surrogates of Protection
M. Elizabeth Halloran, Ira M. Longini, Claudio J. Struchiner

Nyckelord: Statistics, Statistics for Life Sciences, Medicine, Health Sciences, Infectious Diseases