DNA Methylation and Cancer Therapy

1. DNA Methylation
Aharon Razin

2. Epigenetic Mechanisms of Gene Regulation
Keith D. Robertson

3. DNA Hypo- vs. Hypermethylation in Cancer
Melanie Ehrlich, Guanchao Jiang

4. DNA Methylation in Urological Cancers
Wolfgang A. Schulz, Hans-Helge Seifert

5. DNA Methylation in Colorectal Cancer
Jeremy R. Jass, Vicki L. J. Whitehall, Joanne Young, Barbara A. Leggett

6. CpG Island Hypermethylation of Tumor Suppressor Genes in Human Cancer
Michel Herranz, Manel Esteller

7. The Loss of Methyl Groups in DNA of Tumor Cells and Tissues
Alain Niveleau, Chandrika Piyathilake, Adriana Capoa, Claudio Grappelli, Jean-Marc Dumollard, Lucien Frappart, Emmanuel Drouet

8. Identifying Clinicopathological Association of DNA Hypermethylation in Cancers Using CpG Island Microarrays
Susan H. Wei, Timothy T. -C. Yip, Chuan-Mu Chen, Tim H. -M. Huang

9. Methylation Analysis in Cancer
Carolina Haefliger, Sabine Maier, Alexander Olek

10. Regulation of DNA Methyltransferases in Cancer
Nancy Detich, Moshe Szyf

11. Inhibition of Poly(ADP-Ribosyl)ation Allows DNA Hypermethylation
Anna Reale, Giuseppe Zardo, Maria Malanga, Jordanka Zlatanova, Paola Caiafa

12. The Role of Active Demethylation in Cancer and Its Therapeutic Potential
Moshe Szyf, Paul M. Campbell, Nancy Detich, Jing Ni Ou, Stefan Hamm, Veronica Bovenzi

13. Purine Analogues and Their Role in Methylation and Cancer Chemotherapy
Katherine L. Seley, Sylvester L. Mosley

14. DNA Methyltransferase Inhibitors
Gregory K. Reid, A. Robert MacLeod

15. Preclinical and Clinical Studies on 5-Aza-2'-Deoxycytidine, a Potent Inhibitor of DNA Methylation, in Cancer Therapy
Richard L. Momparler

16. Anticancer Gene Therapy by in Vivo DNA Electrotransfer of MBD2 Antisense
Pascal Bigey, Daniel Scherman

17. Epilogue
Moshe Szyf

DRM-restrictions

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Nyckelord: TECHNOLOGY & ENGINEERING / Biomedical TEC059000