Essentials of Thyroid Cancer Management

Part 1..Introduction

1. Basic Thyroid Anatomy
Robert J. Amdur, Ernest L. Mazzaferri

2. Thyroid and Parathyroid Physiology
Ernest L. Mazzaferri, Robert J. Amdur

3. Pathology and Classification Of Thyroid Carcinoma
Heather M. Brown, Robert J. Amdur, Ernest L. Mazzaferri

4. The American Joint Committee on Cancer System of Staging Thyroid Cancer
Robert J. Amdur, Ernest L. Mazzaferri

Part 2..Diagnosis and Imaging of Thyroid Cancer

5. The Diagnosis of Thyroid Cancer
Ernest L. Mazzaferri

6. Definitions: Thyroid Uptake Measurement, Thyroid Scan, and Whole Body Scan
Robert J. Amdur, Ernest L. Mazzaferri

7. Thyroid Stunning
Robert J. Amdur, Ernest L. Mazzaferri

8. The Role of a Diagnostic Radioiodine Whole Body Scan (DxWBS)
Robert J. Amdur, Ernest L. Mazzaferri

9. The Value of a Post-Treatment Whole Body Scan
Robert J. Amdur, Ernest L. Mazzaferri

10. Examples of Radioiodine Whole Body Scans
Robert J. Amdur, Ernest L. Mazzaferri

11. Computerized Tomography (CT) and Magnetic Resonance (MR) Imaging of Thyroid Cancer
Illona M. Schmallfuss, Robert J. Amdur, Douglas B. Villaret, Ernest L. Mazzaferri

12. Positron Emission Tomography (PET) of Thyroid Cancer
Robert J. Amdur, Ernest L. Mazzaferri

13. Neck Ultrasonography in Patients with Thyroid Cancer
Ernest L. Mazzaferri

Part 3..Incidence and Prognosis of Differentiated Thyroid Cancer

14. Incidence, Prevalence, Recurrence, and Mortality of Differentiated Thyroid Cancer
Robert J. Amdur, Ernest L. Mazzaferri

15. Factors that Predict Cancer Recurrence and Death from Differentiated Thyroid Cancer
Robert J. Amdur, Ernest L. Mazzaferri

Part 4..Surgical Therapy of Differentiated Thyroid Cancer

16. A Total Thyroidectomy Rarely Removes All Thyroid Tissue
Douglas B. Villaret, Robert J. Amdur, Ernest L. Mazzaferri

17. Neck Dissections to Remove Malignant Lymph Nodes
Douglas B. Villaret, Robert J. Amdur, Ernest L. Mazzaferri

18. Potential Complications of Thyroid Cancer Surgery
Douglas B. Villaret, Robert J. Amdur, Ernest L. Mazzaferri

Part 5..Medical Therapy of Differentiated Thyroid Cancer

19. Half-Life and Emission Products of I-131
Robert J. Amdur, Ernest L. Mazzaferri

20. Choosing the Activity of I-131 for Therapy
Robert J. Amdur, Ernest L. Mazzaferri

21. Requirements for Outpatient Release Following I-131 Therapy
Robert J. Amdur, George Snyder, Ernest L. Mazzaferri

22. A Checklist of Things to do at the Clinic Visit Prior to I-131 Therapy
Robert J. Amdur, Ernest L. Mazzaferri

23. A Checklist of Things to do on the Day of I-131 Administration
Robert J. Amdur, Ernest L. Mazzaferri

24. Documents that Facilitate I-131 Scheduling and Patient Education
Robert J. Amdur, Ernest L. Mazzaferri

25. The Low-Iodine Diet
Robert J. Amdur, Ernest L. Mazzaferri

26. Intravenous Iodinated Contrast Effects Iodine Uptake for Months
Robert J. Amdur, Ernest L. Mazzaferri

27. Measuring Urinary Iodine (UI)
Robert J. Amdur, Ernest L. Mazzaferri

28. Using Lithium Carbonate to Increase the Effectiveness of I-131
Robert J. Amdur, Ernest L. Mazzaferri

29. Thyroid Hormone Withdrawal to Elevate TSH
Robert J. Amdur, Ernest L. Mazzaferri

30. Recombinant Human TSH: Background Information and Standard Protocol
Robert J. Amdur, Ernest L. Mazzaferri

31. Using rhTSH Prior to I-131 Therapy
Robert J. Amdur, Ernest L. Mazzaferri

32. I-131 Therapy in a Patient with a Small Thyroid Remnant
Robert J. Amdur, Ernest L. Mazzaferri

33. I-131 Therapy in a Patient with a Large Thyroid Remnant
Robert J. Amdur, Ernest L. Mazzaferri

34. Effects of Suppressing Thyrotropin on Tumor Growth and Recurrence
Ernest L. Mazzaferri

35. Potential Side Effects and Complications of I-131 Therapy
Robert J. Amdur, Ernest L. Mazzaferri

36. Management of Xerostomia, Taste Impairment and Dental Prophlaxis
Robert J. Amdur, Pamela L. Sandow, William M. Mendenhall, Ernest L. Mazzaferri

Part 6..Follow-Up Protocol and Treatment of Recurrent or Metastatic Differentiated Thyroid Cancer

37. An Overview of Follow-Up of Differentiated Thyroid Cancer
Ernest L. Mazzaferri

38. Follow-Up of Differentiated Thyroid Cancer Using Serum Thyroglobulin Measurements
Ernest L. Mazzaferri

39. Overview of Management of Differentiated Thyroid Carcinoma in Patients with Negative Whole Body Radioiodine Scans and Elevated Serum Thyroglobulin Levels
Ernest L. Mazzaferri

40. Treatment Guidelines When the Only Evidence of Disease is an Elevated Serum Thyroglobulin Level
Robert J. Amdur, Ernest L. Mazzaferri

41. Treatment of Residual Differentiated Thyroid Cancer in the Neck and Mediastinum
Robert J. Amdur, Ernest L. Mazzaferri

42. Treatment of Lung Metastases from Differentiated Thyroid Cancer
Robert J. Amdur, Ernest L. Mazzaferri

43. Treatment of Bone Metastases from Differentiated Thyroid Cancer
Robert J. Amdur, Ernest L. Mazzaferri

44. Treatment of Spinal Cord Compression from Metastatic Thyroid Cancer
Robert J. Amdur, Ernest L. Mazzaferri

45. Treatment of Brain Metastasis from Differentiated Thyroid Cancer
Robert J. Amdur, Illona M. Schmallfuss, Ernest L. Mazzaferri

Part 7..Differentiated Thyroid Cancer During Pregnancy, in a Thyroglossal Duct, and Unfavorable Histologic Subtypes of DTC

46. Management of Differentiated Thyroid Cancer During Pregnancy
Robert J. Amdur, Ernest L. Mazzaferri

47. Thyroid Cancer Originating in a Thyroglossal Duct Remnant
Robert J. Amdur, Ernest L. Mazzaferri

48. Tall and Collumnar Variants of Papillary Carcinoma
Robert J. Amdur, Ernest L. Mazzaferri

49. Diffuse Sclerosing Variant of Papillary Carcinoma
Robert J. Amdur, Ernest L. Mazzaferri

50. Hürthle Cell Carcinoma
Robert J. Amdur, Ernest L. Mazzaferri

51. Insular and other Poorly Differentiated Thyroid Carcinomas
Robert J. Amdur, Ernest L. Mazzaferri

52. Anaplastic Carcinoma
Robert J. Amdur, Ernest L. Mazzaferri

Part 8..Medullary Thyroid Cancer

53. Diagnosis and Management of Medullary Thyroid Carcinoma
Ernest L. Mazzaferri, Nicole A. Massoll

Part 9..External Beam Radiation Therapy

54. External Beam Radiotherapy Dose Schedules
Robert J. Amdur, Siyong Kim, Jonathan Gang Li, Chiray Liu, William M. Mendenhall, Ernest L. Mazzaferri

55. Indications for External Beam Radiation Therapy for Differentiated Thyroid Cancer
Robert J. Amdur, William M. Mendenhall, Ernest L. Mazzaferri

56. Sequencing of I-131 and External Beam Radiation Therapy for Differentiated Thyroid Cancer
Robert J. Amdur, Ernest L. Mazzaferri

57. Indications for EBRT for Medullary and Anaplastic Thyroid Carcinoma
Robert J. Amdur, William M. Mendenhall, Ernest L. Mazzaferri

58. Conventional Radiotherapy Technique for Treating Thyroid Cancer
Robert J. Amdur, Siyong Kim, Jonathan Gang Li, Chiray Liu, William M. Mendenhall, Ernest L. Mazzaferri

59. Intensity Modulated Radiation Therapy for Thyroid Cancer
Robert J. Amdur, Siyong Kim, Jonathan Gang Li, Chiray Liu, William M. Mendenhall, Ernest L. Mazzaferri

60. Drawing Target Volumes for Intensity Modulated Radiation Therapy for Thyroid Cancer
Robert J. Amdur, Jonathan Gang Li, Siyong Kim, Chiray Liu, William M. Mendenhall, Ernest L. Mazzaferri

61. Potential Toxicity of External Beam Radiotherapy for Thyroid Cancer
Robert J. Amdur, William M. Mendenhall, Ernest L. Mazzaferri

Part 10..Reference Information for Physicians and Patients

62. Resource Websites
Robert J. Amdur, Ernest L. Mazzaferri

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Nyckelord: MEDICAL / Public Health MED078000